Epigenomics of Disease
Genome Biology Collection
The epigenome has been shown to change significantly during progression of diseases and during aging. These epigenetic changes are often shown to be associated with changes in gene expression. Through analysis of these changes, useful biomarkers can be discovered and we can better understand mechanisms of disease progression or cancer heterogeneity.
In this collection, Genome Biology highlights recently published papers related to disease-associated DNA methylation changes.