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Epigenetics and rheumatic diseases

Nan Shen

  1. miRNAs have been shown to play essential regulatory roles in the innate immune system. They function at multiple levels to shape the innate immune response and maintain homeostasis by direct suppression of the...

    Authors: Xiaobing Luo, Koustubh Ranade, Ronel Talker, Bahija Jallal, Nan Shen and Yihong Yao
    Citation: Arthritis Research & Therapy 2013 15:210
  2. Systemic lupus erythematosus is a chronic relapsing autoimmune disease that primarilyafflicts women, and both a genetic predisposition and appropriate environmentalexposures are required for lupus to develop a...

    Authors: Dipak R Patel and Bruce C Richardson
    Citation: Arthritis Research & Therapy 2013 15:201
  3. Mammalian immune responses are intended to eradicate microbial pathogens and thus protect individuals from the harmful effects of such infections. However, unresolved inflammation can be devastating to the hos...

    Authors: Ruozhen Hu and Ryan M O'Connell
    Citation: Arthritis Research & Therapy 2013 15:202