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Risk factors and emerging complications of endocrine disorders

  1. The serine protease inhibitor-1 (SERPINE1) rs1799889 single nucleotide polymorphism (SNP) has been constantly associated with diabetes mellitus (DM) and its vascular complications. The aim of this meta-analysi...

    Authors: JingYi Chen, ChuanNan Zhai, ZhiQian Wang, Rui Li, WenJing Wu, Kai Hou, Mohammad Alzogool, Yan Wang and HongLiang Cong
    Citation: BMC Endocrine Disorders 2021 21:195
  2. Advanced glycation end-products (AGEs) are heterogeneous molecules produced by the non-enzymatic glycation of proteins, lipids, or nucleic acids during hyperglycaemia. Accumulation of AGEs in the peripheral ne...

    Authors: Stella Papachristou, Kalliopi Pafili and Nikolaos Papanas
    Citation: BMC Endocrine Disorders 2021 21:28
  3. Recent study showed that individuals with type 2 diabetes have a high risk of developing colorectal cancer (CRC), in which Receptor for Advanced Glycation End Products (RAGE) plays a pivotal role. We conducted...

    Authors: Xiaohai Zhou, Ning Lin, Mingjie Zhang, Xiaoling Wang, Ye An, Qing Su, Peng Du, Bo Li and Hanbei Chen
    Citation: BMC Endocrine Disorders 2020 20:170
  4. Metabolic syndrome (MetS) is a major public health concern due to its high prevalence and association with heart disease and diabetes. Artificial neural networks (ANN) are emerging as a reliable means of model...

    Authors: Meysam Eyvazlou, Mahdi Hosseinpouri, Hamidreza Mokarami, Vahid Gharibi, Mehdi Jahangiri, Rosanna Cousins, Hossein-Ali Nikbakht and Abdullah Barkhordari
    Citation: BMC Endocrine Disorders 2020 20:169
  5. A growing body of evidence supports neutrophils as having an active role in the development of diabetic kidney disease (DKD). However, the clinical relevance of neutrophils and DKD in autoimmune diabetes remai...

    Authors: Yao Yu, Qiuqiu Lin, Dewei Ye, Yanfei Wang, Binbin He, Yanhua Li, Gan Huang, Zhiguang Zhou and Yang Xiao
    Citation: BMC Endocrine Disorders 2020 20:158
  6. This study tested the association between serum levels of microRNA-486, −146b and -15b and betatrophin in normal and obese children with/without type 2 diabetes mellitus (T2DM).

    Authors: Khalid M. Mohany, Osamah Al rugaie, Osama Al-wutayd, Abdullah Al-Nafeesah and Tahia H. Saleem
    Citation: BMC Endocrine Disorders 2020 20:145
  7. The association between the polymorphisms in the vitamin D receptor (VDR) gene and the risk of type 1 diabetes mellitus (T1DM) has been evaluated in several studies. However, the findings were inconclusive. Thus,...

    Authors: Na Zhai, Ramtin Bidares, Masoud Hassanzadeh Makoui, Saeed Aslani, Payam Mohammadi, Bahman Razi, Danyal Imani, Mohammad Yazdchi and Haleh Mikaeili
    Citation: BMC Endocrine Disorders 2020 20:121
  8. The growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis is critical for the regulation of children’s growth and development. Serum IGF-1 concentrations are usually low in individuals with idiopathic sh...

    Authors: Qianqian Zhao, Mei Zhang, Baolan Ji, Yuntian Chu, Hui Pan, Wenhua Yan and Bo Ban
    Citation: BMC Endocrine Disorders 2020 20:119
  9. Type 2 diabetes mellitus (T2D) is the most frequent type of diabetes. It has a multifactorial etiology, affecting millions of people worldwide. Ghrelin gene (GHRL) encodes the ghrelin peptide, which promotes food...

    Authors: Edgar Alfonso Rivera-León, Mara Anaís Llamas-Covarrubias, Sergio Sánchez-Enríquez, Erika Martínez-López, Mercedes González-Hita and Iris Monserrat Llamas-Covarrubias
    Citation: BMC Endocrine Disorders 2020 20:109
  10. The association between subclinical hypothyroidism (SCH) and metabolic risk factors in the general health examination-based population has been widely explored. However, the results have been inconclusive. Add...

    Authors: Li Jiang, Jinman Du, Weizhu Wu, Jianjiang Fang, Jufang Wang and Jinhua Ding
    Citation: BMC Endocrine Disorders 2020 20:100
  11. Takotsubo syndrome is an uncommon, acute, and reversible cardiomyopathy that occurs primarily in postmenopausal females. The clinical presentation of the syndrome resembles acute coronary syndrome, but coronar...

    Authors: Min Chen, Tong Zhao, Guoping Chen and Shenjiang Hu
    Citation: BMC Endocrine Disorders 2020 20:93
  12. Radioactive iodine (RAI) therapy is an important treatment option for Graves’ disease (GD), the main side effect of RAI treatment is hypothyroidism, and the factors resulting in hypothyroidism are still contro...

    Authors: Rui-Ting Hu, De-Shan Liu and Bin Li
    Citation: BMC Endocrine Disorders 2020 20:76
  13. We quantified, among diabetic adults, the frequency, costs, and factors associated with visits to the emergency department (EDs) and subsequent hospitalizations for acute hypoglycaemic and hyperglycaemic events.

    Authors: Anita Andreano, Marco Bosio and Antonio Giampiero Russo
    Citation: BMC Endocrine Disorders 2020 20:72
  14. Pregnancy-induced Cushing’s syndrome (CS) with an adrenocortical adenoma overexpressing luteinizing hormone (LH)/human choriogonadotropin (hCG) receptors (LHCGR) has been rarely reported in the literatures. Th...

    Authors: Shaohua Li, Chen Yang, Jing Fan, Yao Yao, Xiaomei Lv, Ying Guo and Shaoling Zhang
    Citation: BMC Endocrine Disorders 2020 20:62
  15. Diabetes mellitus (DM) is a global health care problem that can impose a substantial economic burden. Diabetic peripheral neuropathy (DPN) is a common microvascular complication of DM that increases the potent...

    Authors: Wondimeneh Shibabaw Shiferaw, Tadesse Yirga Akalu, Yeshamble Work and Yared Asmare Aynalem
    Citation: BMC Endocrine Disorders 2020 20:49
  16. The voltage-gated potassium channel Kv7.1 encoded by KCNQ1 is located in both cardiac myocytes and insulin producing beta cells. Loss-of-function mutations in KCNQ1 causes long QT syndrome along with glucose-stim...

    Authors: Jinyi Zhang, Christian R. Juhl, Louise Hylten-Cavallius, Morten Salling-Olsen, Allan Linneberg, Jens Juul Holst, Torben Hansen, Jørgen K. Kanters and Signe S. Torekov
    Citation: BMC Endocrine Disorders 2020 20:38
  17. The adipokine adipsin contributes to insulin resistance (IR), inflammation, and obesity, which are all regarded as high-risk factors for mild cognitive impairment (MCI) in patients with type 2 diabetes mellitu...

    Authors: Dan Guo, Yang Yuan, Rong Huang, Sai Tian, Jiaqi Wang, Hongyan Lin, Ke An, Jin Han and Shaohua Wang
    Citation: BMC Endocrine Disorders 2019 19:108