Skip to main content


Emerging investigators

Edited by Timothy O'Brien and Rocky Tuan

An article collection in Stem Cell Research & Therapy.

Emerging Investigators is a collection of articles showcasing the work of early career investigators who have demonstrated growing leadership in the field of stem cells and regenerative medicine, and are within five years of their first independent investigator position. Contributing authors were nominated by members of the Stem Cell Research & Therapy Editorial Board.

This series of articles has not been sponsored. All articles have undergone the journal’s standard peer review process overseen by the Editors-in-Chief. The Editors-in-Chief declare no competing interests.

View all collections published in Stem Cell Research & Therapy

  1. Research

    Pulp regeneration by transplantation of dental pulp stem cells in pulpitis: a pilot clinical study

    Experiments have previously demonstrated the therapeutic potential of mobilized dental pulp stem cells (MDPSCs) for complete pulp regeneration. The aim of the present pilot clinical study is to assess the safe...

    Misako Nakashima, Koichiro Iohara, Masashi Murakami, Hiroshi Nakamura, Yayoi Sato, Yoshiko Ariji and Kenji Matsushita

    Stem Cell Research & Therapy 2017 8:61

    Published on: 9 March 2017

  2. Research

    Exogenous marker-engineered mesenchymal stem cells detect cancer and metastases in a simple blood assay

    Mesenchymal stem cells (MSCs) are adult multipotent stem cells that possess regenerative and immunomodulatory properties. They have been widely investigated as therapeutic agents for a variety of disease condi...

    Linan Liu, Shirley X. Zhang, Rangoli Aeran, Wenbin Liao, Mengrou Lu, George Polovin, Egest J. Pone and Weian Zhao

    Stem Cell Research & Therapy 2015 6:181

    Published on: 21 September 2015

  3. Research

    Local injection of mesenchymal stem cells protects testicular torsion-induced germ cell injury

    Testicular torsion is a urological emergency and infertility is a common complication due to ischemic injury. Surgical reduction and orchiopexy is indicated, but to date there is no effective method for restor...

    Chi-Hao Hsiao, Andrea Tung-Qian Ji, Chih-Cheng Chang, Chien-Jui Cheng, Liang-Ming Lee and Jennifer Hui-Chun Ho

    Stem Cell Research & Therapy 2015 6:113

    Published on: 30 May 2015

  4. Research

    Comparative analysis of mesenchymal stem cell and embryonic tendon progenitor cell response to embryonic tendon biochemical and mechanical factors

    Advances in tendon engineering with mesenchymal stem cells (MSCs) are hindered by a need for cues to direct tenogenesis, and markers to assess tenogenic state. We examined the effects of factors involved in em...

    Jeffrey P Brown, Thomas V Galassi, Matteo Stoppato, Nathan R Schiele and Catherine K Kuo

    Stem Cell Research & Therapy 2015 6:89

    Published on: 9 May 2015

  5. Research

    Endothelial cells direct human mesenchymal stem cells for osteo- and chondro-lineage differentiation through endothelin-1 and AKT signaling

    Human mesenchymal stem cells (hMSCs) reside in a perivascular niche of the body, suggesting that they interact closely with vascular endothelial cells (ECs) through cell-cell interaction or paracrine signaling...

    Tsung-Lin Tsai, Bowen Wang, Matthew W Squire, Lian-Wang Guo and Wan-Ju Li

    Stem Cell Research & Therapy 2015 6:88

    Published on: 1 May 2015

  6. Research

    Gene expression-based enrichment of live cells from adipose tissue produces subpopulations with improved osteogenic potential

    Mesenchymal stem cells have been increasingly used for cell-based therapies. Adipose-derived stem/stromal cells (ASCs) from the stromal vascular fraction (SVF) of fat tissue are a particularly attractive optio...

    Hetal D Marble, Bryan A Sutermaster, Manisha Kanthilal, Vera C Fonseca and Eric M Darling

    Stem Cell Research & Therapy 2014 5:145

    Published on: 6 October 2014