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Towards malaria elimination

The launch of a new thematic series of Malaria Journal, "Towards malaria elimination", creates the forum that allows carrying scientific evidence on how to achieve malaria elimination in specific endemic settings and conditions into the circles of scientists, public health specialists, national and global programme managers, funders and decision makers.

"Towards malaria elimination" welcomes original papers, reviews, commentaries and opinion pieces on malaria elimination and eradication, and hopes that this mix of scientific information and debate will catalyze and dynamize the move towards more intensified control and progressively malaria elimination within a spirit of mutual learning for change. The Editors very much hope that many scientists, public health professionals and policy makers will start using "Towards malaria elimination" as one of their ways to share new evidence or to discuss evidence presented in the scientific literature.

View all collections published in Malaria Journal.

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  1. In 2020, the Zambia National Malaria Elimination Centre targeted the distribution of long-lasting insecticidal nets (LLINs) and indoor-residual spraying (IRS) campaigns based on sub-district micro-planning, wh...

    Authors: Irene Kyomuhangi, Andrew Andrada, Zhiyuan Mao, Derek Pollard, Christina Riley, Adam Bennett, Busiku Hamainza, Hannah Slater, Justin Millar, John M. Miller, Thomas P. Eisele and Kafula Silumbe
    Citation: Malaria Journal 2023 22:365
    Content type: Research Published on:

  2. Dual hrp2/hrp3 genes deletions in P. falciparum isolates are increasingly reported in malaria-endemic countries and can produce false negative RDT results leading to inadequate case management. Data on the freque...

    Authors: Casimire Wendlamita Tarama, Harouna Soré, Mafama Siribié, Siaka Débé, Réné Kinda, Wendyam Gérard Nonkani, Farida Tiendrebeogo, Winnie Bantango, Kassoum Yira, Esther Yéri Hien, Moussa Wandaogo Guelbéogo, Yves Traoré, Didier Ménard and Adama Gansané
    Citation: Malaria Journal 2023 22:363
    Content type: Research Published on:

  3. Plasmodium vivax is the main species responsible for human malaria in Brazil, and one of its manifestations is splenic malaria, though there are still challenges in its diagnosis. The present study aimed to stand...

    Authors: Raimunda Sandra Pacheco Souza, Monique F. dos Reis, Luiz Carlos de Lima Ferreira, Manuela C. Morais, Antonio Kassio S. Lima, Laila Rowena Albuquerque Barbosa, Gisely Cardoso de Melo and Marcus Vinicius Guimaraes de Lacerda
    Citation: Malaria Journal 2023 22:361
    Content type: Research Published on:

  4. Karnataka is one of the largest states in India and has a wide range of geographical terrains, ecotypes, and prevalence of malaria. It experiences a voluminous influx and efflux of people across the state that...

    Authors: Vani Hanumantappa Chalageri, Shrinivasa B. Marinaik, Sujith N. Nath, Richa Singhal, Smita Rawat, Krishnappa Ravikumar, Mahamood Shariff and Alex Eapen
    Citation: Malaria Journal 2023 22:353
    Content type: Research Published on:

  5. Malaria affects millions of Cameroonian children under 5 years of age living in the North and Far North regions. These regions bear the greatest burden, particularly for children under 5 years of age. To reduc...

    Authors: Arnold Fottsoh Fokam, Toussaint Rouamba, Sekou Samadoulougou, Yazoume Ye and Fati Kirakoya-Samadoulougou
    Citation: Malaria Journal 2023 22:347
    Content type: Research Published on:

  6. The efficacy of chloroquine treatment for vivax malaria has been rarely evaluated due to a lack of an appropriate testing method. The objective of this study was to conduct molecular monitoring of chloroquine ...

    Authors: Hongyun Ding, Ying Dong, Yan Deng, Yanchun Xu, Yan Liu, Jing Wu, Mengni Chen, Canglin Zhang, Li Liu and Yingkun Lin
    Citation: Malaria Journal 2023 22:338
    Content type: Research Published on:

  7. The Lao PDR National Strategic Plan for malaria control and elimination for year 2021–2025 emphasizes the importance of routine entomological surveillance being conducted in areas with high transmission and in...

    Authors: Sébastien Marcombe, Santi Maithaviphet, Rita Reyburn, Khamfong Kunlaya, Khambang Silavong, Bouasy Hongvanthong, Viengxay Vanisaveth, Viengphone Sengsavath, Vilasack Banouvong, Keobouphaphone Chindavongsa, Boualam Khamlome and Matthew Shortus
    Citation: Malaria Journal 2023 22:319
    Content type: Research Published on:

  8. Appropriate malaria treatment-seeking behaviour (TSB) is critical for timely detecting malaria, prompt treatment, and prevention of onward transmission of the disease in a community. This study aimed to compar...

    Authors: Jian-Wei Xu, Dao-Wei Deng, Chun Wei, Xing-Wu Zhou and Jian-Xiong Li
    Citation: Malaria Journal 2023 22:309
    Content type: Research Published on:

  9. Imperfect adherence is a major barrier to effective primaquine radical cure of Plasmodium vivax. This study investigated the effect of reduced adherence on the risk of P. vivax recurrence.

    Authors: Parinaz Mehdipour, Megha Rajasekhar, Saber Dini, Sophie Zaloumis, Tesfay Abreha, Ishag Adam, Ghulam Rahim Awab, J. Kevin Baird, Larissa W. Brasil, Cindy S. Chu, Liwang Cui, André Daher, Margarete do Socorro M Gomes, Lilia Gonzalez‑Ceron, Jimee Hwang, Harin Karunajeewa…
    Citation: Malaria Journal 2023 22:306
    Content type: Research Published on:

  10. Plasmodium vivax malaria is considered a major threat to malaria eradication. The radical cure for P. vivax malaria normally requires a 14-day administration of primaquine (PQ) to clear hypnozoites. However, main...

    Authors: Kyawt Mon Win, Pyae Linn Aung, Zau Ring, Nay Yi Yi Linn, Myat Phone Kyaw, Wang Nguitragool, Liwang Cui, Jetsumon Sattabongkot and Saranath Lawpoolsri
    Citation: Malaria Journal 2023 22:302
    Content type: Research Published on:

  11. Strengthening malaria control activities in Tanzania has dramatically declined human malaria infections. However, there is an increasing epidemiological shift in the burden on school-age children. The underlyi...

    Authors: Fadhila Kihwele, Tegemeo Gavana, Christina Makungu, Hajirani M. Msuya, Yeromin P. Mlacha, Nicodem James Govella, Prosper Pius Chaki and Bruno Fokas Sunguya
    Citation: Malaria Journal 2023 22:293
    Content type: Research Published on:

  12. Larval Source Management (LSM) is an important tool for malaria vector control and is recommended by WHO as a supplementary vector control measure. LSM has contributed in many successful attempts to eliminate ...

    Authors: Andy Hardy, Khamis Haji, Faiza Abbas, Juma Hassan, Abdullah Ali, Yussuf Yussuf, Jackie Cook, Laura Rosu, Arnon Houri-Yafin, Arbel Vigodny, Gregory Oakes, Silas Majambere and Eve Worrall
    Citation: Malaria Journal 2023 22:286
    Content type: Research Published on:

  13. Malaria remains a major public health concern around the world, particularly in resource-constrained countries. Malaria still accounts for 40% of all Out-Patient Department (OPD) cases in Ghana, with children ...

    Authors: Prince Adum, Veronica Adwoa Agyare, Joseph Owusu-Marfo and Yaa Nyarko Agyeman
    Citation: Malaria Journal 2023 22:268
    Content type: Research Published on:

  14. Malaria was once widespread in Guangzhou, China. However, a series of control measures have succeeded in eliminating local malaria infections. Based on the analysis of the characteristics of malaria epidemics ...

    Authors: Yuehua Chen, Hao Zhang, Haiyan Chen, Lirui Fan, Conghui Xu, Jianmin Xu, Shouyi Chen, Kuncai Chen and Yuehong Wei
    Citation: Malaria Journal 2023 22:265
    Content type: Research Published on:

  15. Despite significant efforts made to control malaria in Ethiopia, the disease remains one of the top public health problems in the country. Baseline malaria prevalence and associated factor at high malaria area...

    Authors: Yosef Yohanes Lakew, Anteneh Fikrie, Sisay Bedane Godana, Fatuma Wariyo and Wongelawit Seyoum
    Citation: Malaria Journal 2023 22:259
    Content type: Research Published on:

  16. Malaria remains a major public health concern in The Gambia. The study assessed the trend of malaria admissions and outcome of adult patients admitted after the start of the COVID-19 pandemic in a tertiary hos...

    Authors: Sheikh Omar Bittaye, Abubacarr Jagne, Lamin E. S. Jaiteh, Alfred Amambua-Ngwa, Abdul Karim Sesay, Bertha Ekeh, Behzad Nadjm, Williams Estrada Ramirez, Asmell Ramos, Basil Okeahialam, Emmanuel Effa, Ousman Nyan and Ramou Njie
    Citation: Malaria Journal 2023 22:253
    Content type: Research Published on:

  18. To enhance malaria elimination, Vietnam adopted a Reactive Surveillance and Response (RASR) Strategy in which malaria case notification and investigation must be completed within 2 days followed by a focus inv...

    Authors: Win Han Oo, Xuan Thang Nguyen, Thi Van Anh Ngo, Duc Thang Ngo, Win Htike, Nilar Aye Tun, Kaung Myat Thu, Julia Cutts, T Hong Phuc Nguyen, May Chan Oo, Ei Phyu Htwe, Aung Khine Zaw, Katherine O’Flaherty, Paul A. Agius and Freya J. I. Fowkes
    Citation: Malaria Journal 2023 22:229
    Content type: Research Published on:

  19. Malaria, transmitted by the bite of infective female Anopheles mosquitoes, remains a global public health problem. The presence of invasive Anopheles stephensi, capable of transmitting Plasmodium vivax and Plasmo...

    Authors: Abebe Teshome, Berhanu Erko, Lemu Golassa, Gedeon Yohannes, Seth R. Irish, Sarah Zohdy, Melissa Yoshimizu and Sisay Dugassa
    Citation: Malaria Journal 2023 22:218
    Content type: Research Published on:

  20. Chloroquine (CQ) has been the preferred clinical treatment for vivax malaria in Yunnan Province since 1958, with over 300,000 patients. This study aimed to help make trend predictions regarding variations the ...

    Authors: Hongyun Ding, Ying Dong, Yan Deng, Yanchun Xu, Yan Liu, Jing Wu, Mengni Chen, Canglin Zhang and Weibin Zheng
    Citation: Malaria Journal 2023 22:181
    Content type: Research Published on:

  21. The reliance on blood for thin and thick blood smear microscopy—using a relatively invasive procedure has presented challenges to the use of reliable diagnostic tests in non-clinical settings at the point-of-n...

    Authors: John Diaz, Cody Gusto, Kaci McCoy, Colby Silvert, Joseph A. Bala, Joseph Atibu, Antoinette Tshefu, Melchior Mwandagalirwa and Rhoel R. Dinglasan
    Citation: Malaria Journal 2023 22:180
    Content type: Research Published on:

  22. Pfcrt gene has been associated with chloroquine resistance and the pfmdr1 gene can alter malaria parasite susceptibility to lumefantrine, mefloquine, and chloroquine. In the absence of chloroquine (CQ) and extens...

    Authors: Geletta Tadele, Aminata Jawara, Mary Oboh, Eniyou Oriero, Sisay Dugassa, Alfred Amambua-Ngwa and Lemu Golassa
    Citation: Malaria Journal 2023 22:171
    Content type: Research Published on:

  24. Indoor residual spraying (IRS) has been the main tool used to control malaria. Reducing the life span and the density of the vector mosquitoes are direct effects of IRS towards restricting malaria transmission...

    Authors: Medina Ibrahim, Hunachew Beyene, Alemu Tolcha, Habtamu Eskendir and Abiyu Ayalew Assefa
    Citation: Malaria Journal 2023 22:144
    Content type: Research Published on:

  25. Measuring risk of malaria transmission is complex, especially in case of Plasmodium vivax. This may be overcome using membrane feeding assays in the field where P. vivax is endemic. However, mosquito-feeding assa...

    Authors: Andargie Abate, Jifar Hassen, Laurent Dembele, Didier Menard and Lemu Golassa
    Citation: Malaria Journal 2023 22:136
    Content type: Research Published on:

  27. Malaria remains one of the main causes of morbidity and mortality in Cameroon. To inform vector control intervention decision making, malaria vector surveillance was conducted monthly from October 2018 to Sept...

    Authors: Etienne Fondjo, Jean-Claude Toto, Magellan Tchouakui, Wolfgang Ekoko Eyisap, Salomon Patchoke, Benjamin Menze, Boris Njeambosay, Francis Zeukeug, Raymond Tabue Ngomdjum, Elysée Mandeng, Emmanuel Elanga-Ndille, Edmond Kopya, Jerome Achille Binyang, Cyrille Ndo, Billy Tene-Fossog, Armel Tedjou…
    Citation: Malaria Journal 2023 22:123
    Content type: Research Published on:

  28. SMC was adopted in Nigeria in 2014 and by 2021 was being implemented in 18 states, over four months between June and October by 143000 community drug distributors (CDDs) to a target population of 23million chi...

    Authors: Nnenna Ogbulafor, Perpetua Uhomoibhi, Emmanuel Shekarau, Jamilu Nikau, Chukwu Okoronkwo, Nadia M. L. Fanou, Ibrahima Marietou Mbaye, Jean-Louis Ndiaye, Andre-Marie Tchouatieu, Abena Poku-Awuku, Corinne Merle, Susana Scott, Paul Milligan, Aminu Ali, Hauwa’u Evelyn Yusuf, Stephen Oguche…
    Citation: Malaria Journal 2023 22:120
    Content type: Research Published on:

  29. Malaria remains a major public health concern in Cameroon. Understanding vector distribution and malaria transmission dynamics is of paramount importance for evaluating the performance of control strategies. T...

    Authors: Nelly Armanda Kala Chouakeu, Timoléon Tchuinkam, Roland Bamou, Mabu Maxim Bindamu, Abdou Talipouo, Edmond Kopya, Parfait Awono-Ambene and Christophe Antonio-Nkondjio
    Citation: Malaria Journal 2023 22:116
    Content type: Research Published on:

  30. Malaria remains a main parasitic disease of humans. Although the largest number of cases is reported in the African region, there are still endemic foci in the Americas. Central America reported 36,000 malaria...

    Authors: Gabriela Matamoros, Denis Escobar, Alejandra Pinto, Delmy Serrano, Eliška Ksandrová, Nicole Grimaldi, Gabriel Juárez-Fontecha, Marcela Moncada, Hugo O. Valdivia and Gustavo Fontecha
    Citation: Malaria Journal 2023 22:110
    Content type: Research Published on:

  31. Malaria is still one of the major infectious diseases affecting human health, and the World Health Organization (WHO) has attached special importance to malaria-related technical training for its global elimin...

    Authors: Cheng Liang, Xuedan Ke, Yuanyuan Cao, Weiming Wang, Mengmeng Yang, Jie Wang, Cecilia T. Hugo, Leonard Ortega, Glenda Gonzales, Guoding Zhu and Jun Cao
    Citation: Malaria Journal 2023 22:90
    Content type: Research Published on:

  32. Anopheles farauti is one of the major vectors of malaria in the Southwest Pacific region and is responsible for past outbreaks in Australia. With an adaptable biting profile conducive to behavioural resistance to...

    Authors: Weng K. Chow, Nigel W. Beebe, Luke Ambrose, Paul Pickering and Robert D. Cooper
    Citation: Malaria Journal 2023 22:85
    Content type: Research Published on:

  33. In western Kenya, not all malaria cases are reported as stipulated in the community case management of malaria (CCMm) strategy. This underreporting affects the equity distribution of malaria commodities and th...

    Authors: Wilfred Ouma Otambo, Kevin O. Ochwedo, Collince J. Omondi, Ming-Chieh Lee, Chloe Wang, Harrysone Atieli, Andew K. Githeko, Guofa Zhou, James Kazura, John Githure and Guiyun Yan
    Citation: Malaria Journal 2023 22:83
    Content type: Research Published on:

  34. Some anti-malarial drugs often cause haemolytic anaemia in glucose-6-phosphate-dehydrogenase deficiency (G6PDd) patients. This study aims to analyse the association of G6PDd and anaemia in malaria patients rec...

    Authors: Erni J. Nelwan, Sharifah Shakinah and Adeline Pasaribu
    Citation: Malaria Journal 2023 22:77
    Content type: Review Published on:

  35. Since 2004, malaria transmission on Bioko Island has declined significantly as a result of the scaling-up of control interventions. The aim of eliminating malaria from the Island remains elusive, however, unde...

    Authors: Guillermo A. García, Mark Janko, Dianna E. B. Hergott, Olivier T. Donfack, Jordan M. Smith, Jeremías Nzamío Mba Eyono, Kylie R. DeBoer, Restituto Mba Nguema Avue, Wonder P. Phiri, Edward M. Aldrich, Christopher Schwabe, Thomas C. Stabler, Matilde Riloha Rivas, Ewan Cameron, Carlos A. Guerra, Jackie Cook…
    Citation: Malaria Journal 2023 22:72
    Content type: Research Published on:

  36. Malaria is a major public health issue with substantial risks among vulnerable populations. Currently, the World Health Organization (WHO) recommends SP-IPTp in the second and third trimesters. However, the ef...

    Authors: Adebanjo J. Adegbola, Omotade A. Ijarotimi, Akaninyene E. Ubom, Bukola A. Adesoji, Olajide E. Babalola, Emma F. Hocke, Helle Hansson, Andria Mousa, Oluseye O. Bolaji, Michael Alifrangis and Cally Roper
    Citation: Malaria Journal 2023 22:71
    Content type: Research Published on:

  37. Malaria, transmitted by the bite of infective female Anopheles mosquitoes, remains a global public health problem. The presence of an invasive Anopheles stephensi, capable of transmitting Plasmodium vivax and Pla...

    Authors: Abebe Teshome, Berhanu Erko, Lemu Golassa, Gedeon Yohannes, Seth R. Irish, Sarah Zohdy and Sisay Dugassa
    Citation: Malaria Journal 2023 22:48
    Content type: Research Published on:

    The Correction to this article has been published in Malaria Journal 2023 22:312

  38. Mass distributions of long-lasting insecticidal nets (LLINs) have contributed to large reductions in the malaria burden. However, this success is in jeopardy due in part to the increasing pyrethroid-resistant ...

    Authors: Emmanuel Mbuba, Olukayode G. Odufuwa, Jason Moore, Selemani Mmbaga, Emile Tchicaya, Constant Edi, Vani Chalageri, Sreehari Uragayala, Amit Sharma, Manju Rahi, Kamaraju Raghavendra, Alex Eapen, Hannah Koenker, Amanda Ross and Sarah J. Moore
    Citation: Malaria Journal 2023 22:30
    Content type: Methodology Published on:

  39. Malaria is a leading cause of outpatient visits and deaths among children in Guinea. Despite several mass distribution campaigns of insecticide-treated nets (ITNs) in Guinea, ITN ownership and use remain low. ...

    Authors: Ousmane Oumou Diallo, Ifeoma D. Ozodiegwu, Alioune Camara, Beatriz Galatas and Jaline Gerardin
    Citation: Malaria Journal 2023 22:29
    Content type: Research Published on:

  40. Malaria infection during pregnancy is a significant public health problem that puts pregnant women at risk. Interruption of transmission of asymptomatic malaria among a population remained a challenge and the ...

    Authors: Fufa Balcha, Takele Menna and Fantu Lombamo
    Citation: Malaria Journal 2023 22:28
    Content type: Research Published on:

  41. Declining efficacy of chloroquine for the treatment Plasmodium vivax malaria has been reported in different endemic settings in Ethiopia. This highlights the need to assess alternative options for P. vivax treatm...

    Authors: Hussein Mohammed, Heven Sime, Henok Hailgiorgis, Melkie Chernet, Mihreteab Alebachew, Hiwot Solomon, Gudissa Assefa, Mebrahtom Haile, Samuel Girma, Worku Bekele, Geremew Tasew, Bokretsion Gidey, Robert J. Commons and Ashenafi Assefa
    Citation: Malaria Journal 2022 21:401
    Content type: Research Published on:

  42. Clandestine gold miners remain key hosts for malaria in French Guiana (FG) and contribute to imported malaria cases in Suriname and Brazil. The Malakit intervention, implemented in FG borders with Suriname and...

    Authors: Cécile Longchamps, Muriel Suzanne Galindo, Yann Lambert, Alice Sanna, Louise Mutricy, Laure Garancher, Antoine Adenis, Mathieu Nacher, Martha Suarez-Mutis, Hedley Cairo, Helen Hiwat, Stephen Vreden and Maylis Douine
    Citation: Malaria Journal 2022 21:397
    Content type: Research Published on:

  43. The use of insecticide-treated bed nets has been proven to be effective in reducing malaria transmission in highly endemic areas. Use of long-lasting insecticidal nets (LLINs) has been embraced by many malaria...

    Authors: Anne Ruth Akello, John Paul Byagamy, Samuel Etajak, Charles Stephen Okadhi and Adoke Yeka
    Citation: Malaria Journal 2022 21:363
    Content type: Research Published on:

  44. Endemic malaria is present in all 15 municipalities of Roraima state, Brazilian Amazonia. Knowledge of epidemiological data of specific populations can guide health policies to formulate effective strategies f...

    Authors: Jacqueline de Aguiar Barros, Fabiana Granja, Pedro Pequeno, Paola Marchesini and Maria de Fátima Ferreira da Cruz
    Citation: Malaria Journal 2022 21:358
    Content type: Case Study Published on:

  45. Haemoglobinopathies and G6PD deficiency are inherited disorders found mostly in malaria-endemic areas among different tribal groups of India. However, epidemiological data specific to Particularly Vulnerable T...

    Authors: Sujata Dixit, Arundhuti Das, Ramakanta Rana, Hemant K. Khuntia, Akhil B. Ota, Sanghamitra Pati, Madhusmita Bal and Manoranjan Ranjit
    Citation: Malaria Journal 2022 21:340
    Content type: Research Published on:

  46. Despite several efforts at addressing the barriers to adherence to the WHO-supported test, treat and track (T3) malaria case management guideline in Ghana, adherence remains a challenge. This study explored th...

    Authors: Augusta Soninour Kolekang, Yaw Afrane, Stephen Apanga, Dejan Zurovac, Anthony Kwarteng, Samuel Afari-Asiedu, Kwaku Poku Asante and Anthony Danso-Appiah
    Citation: Malaria Journal 2022 21:332
    Content type: Research Published on:

  47. Gametocytes are the sexual stages ensuring continuity of the development cycle of the parasite, as well as its transmission to humans. The efficacy of artemisinin-based anti-malarials against asexual stages of Pl...

    Authors: Malalanandrianina A. Rakotoarisoa, Jocia Fenomanana, Bronislaw Tchesterico Dodoson, Voahangy Hanitriniaina I. Andrianaranjaka and Arsène Ratsimbasoa
    Citation: Malaria Journal 2022 21:331
    Content type: Research Published on:

  49. Broflanilide is a newly discovered insecticide with a novel mode of action targeting insect γ-aminobutyric acid receptors. The efficacy of VECTRON™ T500, a wettable powder formulation of broflanilide, was assesse...

    Authors: Renaud Govoetchan, Augustin Fongnikin, Thomas Syme, Graham Small, Martial Gbegbo, Damien Todjinou, Mark Rowland, Derric Nimmo, Germain Gil Padonou and Corine Ngufor
    Citation: Malaria Journal 2022 21:324
    Content type: Research Published on: