Early-onset dementia

What can we learn from study of Alzheimer's disease in patients with Down syndrome for early-onset Alzheimer's disease in the general population?

The clinical and scientific study of dementia in adults with Down syndrome led to the development of the amyloid hypothesis as a fundamental concept in Alzheimer's disease pathogenesis. The journey started wit...

Authors: Robyn A Wallace and Arthur J Dalton

Citation: Alzheimer's Research & Therapy 2011 3:13

Content type: Review Published on: 19 April 2011
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Should EOAD patients be included in clinical trials?

Alzheimer disease (AD) is a devastating neurodegenerative disease affecting 1 in 68 in the population. An arbitrary cutoff 65 years as the age of onset to distinguish between early- and late-onset AD has been ...

Authors: Kinga Szigeti and Rachelle S Doody

Citation: Alzheimer's Research & Therapy 2011 3:4

Content type: Review Published on: 8 February 2011
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