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Disease Neurogenomics

Guest editors: Joseph Buxbaum and Catalina Betancur

Disease NeurogenomicsGenome Medicine is pleased to present a special issue on Disease Neurogenomics. The issue captures the advances made in understanding the impact of genetic and genomic variation on neuronal function, networks and the transition to dysregulation, with a special focus on neurodevelopmental, neuropsychiatric and neurodegenerative diseases.

This collection of articles has not been sponsored and articles have undergone the journal’s standard peer-review process. The Guest editors declare that they have no competing interests.

  1. Content type: Research

    Amyotrophic lateral sclerosis (ALS) is a progressive neurological disease characterised by the degeneration of motor neurons, which are responsible for voluntary movement. There remains limited understanding o...

    Authors: Jacob Gratten, Qiongyi Zhao, Beben Benyamin, Fleur Garton, Ji He, Paul J. Leo, Marie Mangelsdorf, Lisa Anderson, Zong-Hong Zhang, Lu Chen, Xiang-Ding Chen, Katie Cremin, Hong-Weng Deng, Janette Edson, Ying-Ying Han, Jessica Harris…

    Citation: Genome Medicine 2017 9:97

    Published on:

  2. Content type: Comment

    Genome-wide association studies have made strides in identifying common variation associated with disease. The modest effect sizes preclude risk prediction based on single genetic variants, but polygenic risk ...

    Authors: Cathryn M. Lewis and Evangelos Vassos

    Citation: Genome Medicine 2017 9:96

    Published on: