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In the accumulation of information, databases play a pivotal role for biomedical scientists. This topical series is a collection of descriptions of databases that provided a comprehensive compilation of data for research purposes.

Dr Miguel A Andrade-Navarro, Dr Carolina Perez-Iratxeta

  1. Aedes aegypti is the principal vector of dengue and yellow fever viruses. The availability of the sequenced and annotated genome enables genome-wide analyses of gene expression in this mosquito. The large amount ...

    Authors: Sumudu N Dissanayake, Jose MC Ribeiro, Mei-Hui Wang, William A Dunn, Guiyun Yan, Anthony A James and Osvaldo Marinotti
    Citation: BMC Research Notes 2010 3:248
  2. Rapid growth in the scientific literature available on-line continues to motivate shifting data analysis from humans to computers. For example, greater knowledge of sentence characteristics indicative of inter...

    Authors: Michael A Bauer, Robert E Belford, Jing Ding and Daniel Berleant
    Citation: BMC Research Notes 2010 3:122
  3. The integration of information present in many disparate biological databases represents a major challenge in biomedical research. To define the problems and needs, and to explore strategies for database integ...

    Authors: Michael Gruenberger, Rudi Alberts, Damian Smedley, Morris Swertz, Paul Schofield and Klaus Schughart
    Citation: BMC Research Notes 2010 3:16
  4. Consolidating transcriptome data of non-human primates is essential to annotate primate genome sequences, and will facilitate research using non-human primates in the genomic era. Macaca fascicularis is a macaque...

    Authors: Naoki Osada, Makoto Hirata, Reiko Tanuma, Yutaka Suzuki, Sumio Sugano, Keiji Terao, Jun Kusuda, Yosuke Kameoka, Katsuyuki Hashimoto and Ichiro Takahashi
    Citation: BMC Research Notes 2009 2:199
  5. Protein Post-Translational Modification (PTM) plays an essential role in cellular control mechanisms that adjust protein physical and chemical properties, folding, conformation, stability and activity, thus al...

    Authors: Tzong-Yi Lee, Justin Bo-Kai Hsu, Wen-Chi Chang, Ting-Yuan Wang, Po-Chiang Hsu and Hsien-Da Huang
    Citation: BMC Research Notes 2009 2:111
  6. Oxygenases belong to the oxidoreductive group of enzymes (E.C. Class 1), which oxidize the substrates by transferring oxygen from molecular oxygen (O2) and utilize FAD/NADH/NADPH as the co-substrate. Oxygenases c...

    Authors: Pankaj K Arora, Manish Kumar, Archana Chauhan, Gajendra PS Raghava and Rakesh K Jain
    Citation: BMC Research Notes 2009 2:67
  7. Currently one of the largest online repositories for human and mouse stem cell gene expression data, StemBase was first designed as a simple web-interface to DNA microarray data generated by the Canadian Stem ...

    Authors: Reatha Sandie, Gareth A Palidwor, Matthew R Huska, Christopher J Porter, Paul M Krzyzanowski, Enrique M Muro, Carolina Perez-Iratxeta and Miguel A Andrade-Navarro
    Citation: BMC Research Notes 2009 2:39
  8. Some mutations in the internal regions of exons occur within splicing enhancers and silencers, influencing the pattern of alternative splicing in the corresponding genes. To understand how these sequence chang...

    Authors: Jason M Bechtel, Preeti Rajesh, Irina Ilikchyan, Ying Deng, Pankaj K Mishra, Qi Wang, Xiaochun Wu, Kirill A Afonin, William E Grose, Ye Wang, Sadik Khuder and Alexei Fedorov
    Citation: BMC Research Notes 2008 1:3