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Call for papers - Cardiac and vascular tissue engineering and regeneration

Guest Editors

Tamer M. A. Mohamed, PhD, Baylor College of Medicine, USA 
Huaxiao “Adam” Yang, PhD, University of North Texas Biomedical Engineering, USA

Submission Status: Open   |   Submission Deadline: 30 June 2025

BMC Cardiovascular Disorders calls for submissions to a new article Collection on Cardiac and vascular tissue engineering and regeneration. Researchers in this multidisciplinary field are working to develop strategies for repairing and regenerating cardiovascular tissue. Significant advancements in our understanding of stem cell biology and biomaterials have paved the way for testing the regenerative potential of stem cell-derived cardiovascular cell types. These approaches include direct injections and the creation of engineered tissues in vitro for cardiac and vascular repair.

New Content ItemThis Collection supports and amplifies research related to SDG 3: Good Health & Wellbeing.

Meet the Guest Editors

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Tamer M. A. Mohamed, PhD, Baylor College of Medicine, USA

Dr Tamer M. A. Mohamed, PhD, has broad expertise in molecular cardiology and drug screening in addition to cardiac regeneration and epigenetics. During his research endeavors, he studied novel mechanisms and therapies for cardiac hypertrophy and heart failure. His research had a major impact on two approaches for endogenous heart repair: direct cardiac reprogramming and inducing cardiomyocyte proliferation. Most recently, his laboratory established a novel system for long-term culture of human and pig heart slices and efficiently demonstrated the efficacy of new cardiac regenerative therapies in such pre-clinical models. This technology has opened a new avenue of research to explore pathophysiological mechanisms and toxicities in primary pig and human heart tissues.

Huaxiao “Adam” Yang, PhD, University of North Texas Biomedical Engineering, USA

Dr Huaxiao “Adam” Yang is an Assistant Professor (tenure-track) in the Department of Biomedical Engineering (BME) at the University of North Texas. He was trained as a postdoctoral fellow at the Stanford University Cardiovascular Institute on cardiovascular biology and stem cell technology. Before that, he received his PhD in the Department of Bioengineering at Clemson University focusing on advanced bioengineering technologies in the field of cardiovascular tissue engineering for studying human cardiovascular development and disease. Dr Yang’s research lab focuses on building the next-generation bioengineering system for modeling cardiovascular development and diseases through synergizing emerging biomedical technologies, such as human pluripotent stem cells, 3D cell culture (e.g., engineering heart tissue and organoid), organ-on-chip, OMICS, and artificial intelligence.

About the Collection

BMC Cardiovascular Disorders calls for submissions to a new article Collection on Cardiac and vascular tissue engineering and regeneration. Across this multidisciplinary field, researchers are helping to develop strategies to repair and regenerate cardiovascular tissue. There has been much progress in our understanding of stem cell biology and biomaterials, leading to groups testing the regenerative potential of stem cell derived cardiovascular cell types for cardiac and vascular tissue repair via direct injection or in the form of in vitro engineered tissues.

In support of SDG 3: Good Health & Well-being, this Collection seeks contributions that address a spectrum of topics, including but not limited to:

• How do you ensure transplanted cells/ engineered tissue establish functional connections with host tissue?

• How do you make cells properly mature outside the body for therapeutic purposes?

• How do you direct and deliver stem cells/ engineered tissue to sites where they are needed?

• How do we prevent the loss of transplanted cells/ engineered tissue after delivery? 

• What physiological, mechanical and biochemical cues must we consider when developing therapeutic interventions?

• How can developmental biology and angiogenesis knowledge be applied in regenerative medicine for cardiovascular disorders?

Image credit: © Pitchy / stock.adobe.com

There are currently no articles in this collection.

Submission Guidelines

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This Collection welcomes submission of original Research Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Cardiac and vascular tissue engineering and regeneration" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.