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Cullin E3 ligases

Featured reviews collection: Cullin ligase regulation

This thematic series  published in Cell Division  covers the role of Cullin-E3 ligases and their regulation.  In this series, the following topics are covered in detail:

  • Cullin based E3 ligases (Cullin1, Cullin 2, Cullin 3, Cullin 4, Cullin 5, Cullin 7)
  • APC E3 ligases
  • CRL and autophagy
  • Neddylation in cancer therapies

Guest Editors:  Wenyi Wei, Ingrid Wertz and Yi Sun

This collection of articles has not been sponsored and articles have undergone the journal's standard peer-review process. The Guest Editors declare no competing interests.

  1. Cullin-RING ligases (CRLs), the largest E3 ubiquitin ligase family, promote ubiquitination and degradation of various cellular key regulators involved in a broad array of physiological and pathological process...

    Authors: Danrui Cui, Xiufang Xiong and Yongchao Zhao
    Citation: Cell Division 2016 11:8
  2. The suppressor of cytokine signaling (SOCS) box consists of the BC box and the cullin 5 (Cul5) box, which interact with Elongin BC and Cul5, respectively. SOCS box-containing proteins have ubiquitin ligase act...

    Authors: Fumihiko Okumura, Akiko Joo-Okumura, Kunio Nakatsukasa and Takumi Kamura
    Citation: Cell Division 2016 11:1