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Credelio

Credelio™ (lotilaner): A comprehensive manuscript collection covering safety, onset of action and spectrum of activity of the newest isoxazoline ectoparasiticide.

New Content Item​​​​​​​This collection of manuscripts has been created in order to provide veterinarians and parasitologists with a substantial amount of scientific data around the use of Credelio (lotilaner) for the treatment of common ectoparasites that can infest pets and their homes around the world.

Ticks and fleas are common parasites of pets that may not only be a nuisance, but also create significant harm and can spread diseases like ehrlichiosis, babesiosis, borreliosis and bartonellosis. Large numbers of ticks or fleas can cause anemia. Immune response to the presence of fleas may even lead to the development of Flea Allergy Dermatitis (FAD).

The articles in this collection report the results of studies funded by Elanco Animal Health during the development of Credelio (lotilaner), providing information regarding its use for the treatment of a variety of ectoparasite species. Detailed conflict of interest statements are included within each article.

The articles in this collection have undergone the journal’s standard peer-review process overseen by the Editors, and each article can also be found individually in the journal. The Editors declare no competing interests.

EDITORIAL
Lotilaner - a novel systemic tick and flea control product for dogs
Susan E. Little

Parasites & Vectors 2017 10:539
Published on: 1 November 2017

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RESEARCH
A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio™) in eliminating fleas in client-owned dogs in the USA
Daniela Karadzovska, Kimberly Chappell, Shane Coble, Martin Murphy, Daniela Cavalleri, Scott Wiseman, Jason Drake and Steve Nanchen

Parasites & Vectors 2017 10:528
Published on: 1 November 2017

Full Text          > PDF


RESEARCH
The novel isoxazoline ectoparasiticide lotilaner (Credelio™): a non-competitive antagonist specific to invertebrates γ-aminobutyric acid-gated chloride channels (GABACls)
Lucien Rufener, Vanessa Danelli, Daniel Bertrand and Heinz Sager

Parasites & Vectors 2017 10:530
Published on: 1 November 2017

Full Text          > PDF


RESEARCH
A randomized, controlled study to assess the efficacy and safety of lotilaner (Credelio™) in controlling ticks in client-owned dogs in Europe
Daniela Cavalleri, Martin Murphy, Wolfgang Seewald, Jason Drake and Steve Nanchen

Parasites & Vectors 2017 10:531
Published on: 1 November 2017

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RESEARCH
A randomised, blinded, controlled field study to assess the efficacy and safety of lotilaner tablets (Credelio™) in controlling fleas in client-owned dogs in European countries
Daniela Cavalleri, Martin Murphy, Wolfgang Seewald, Jason Drake and Steve Nanchen

Parasites & Vectors 2017 10:526
Published on: 1 November 2017

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RESEARCH
Two randomized, controlled studies to assess the efficacy and safety of lotilaner (Credelio™) in preventing Dermacentor reticulatus transmission of Babesia canis to dogs
Daniela Cavalleri, Martin Murphy, Wolfgang Seewald, Jason Drake and Steve Nanchen

Parasites & Vectors 2017 10:520
Published on: 1 November 2017

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RESEARCH
Assessment of the speed of flea kill of lotilaner (Credelio™) throughout the month following oral administration to dogs
Daniela Cavalleri, Martin Murphy, Wolfgang Seewald, Jason Drake and Steve Nanchen

Parasites & Vectors 2017 10:529
Published on: 1 November 2017

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RESEARCH
The intravenous and oral pharmacokinetics of lotilaner in dogs
Céline E. Toutain, Wolfgang Seewald and Martin Jung

Parasites & Vectors 2017 10:522
Published on: 1 November 2017

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RESEARCH
Safety evaluation of lotilaner in dogs after oral administration as flavoured chewable tablets (Credelio™)
Emmanuelle A. Kuntz and Srinivas Kammanadiminti

Parasites & Vectors 2017 10:538
Published on: 1 November 2017

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RESEARCH
Laboratory evaluations of the immediate and sustained effectiveness of lotilaner (Credelio™) against three common species of ticks affecting dogs in Europe
Daniela Cavalleri, Martin Murphy, Regina Lizundia Gorbea, Wolfgang Seewald, Jason Drake and Steve Nanchen

Parasites & Vectors 2017 10:527
Published on: 1 November 2017

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RESEARCH
Efficacy of lotilaner (Credelio™), a novel oral isoxazoline against naturally occurring mange mite infestations in dogs caused by Demodex spp.
Daniel E. Snyder, Scott Wiseman and Julian E. Liebenberg

Parasites & Vectors 2017 10:532
Published on: 1 November 2017

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RESEARCH
Laboratory evaluation of the speed of kill of lotilaner (Credelio™) against Ixodes ricinus ticks on dogs
Martin Murphy, Daniela Cavalleri, Wolfgang Seewald, Jason Drake and Steve Nanchen

Parasites & Vectors 2017 10:541
Published on: 1 November 2017

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RESEARCH
Assessment of the onset of lotilaner (Credelio™) speed of kill of fleas on dogs
Daniela Cavalleri, Martin Murphy, Wolfgang Seewald, Jason Drake and Steve Nanchen

Parasites & Vectors 2017 10:521
Published on: 1 November 2017

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RESEARCH
Laboratory evaluations of the immediate and sustained efficacy of lotilaner (Credelio™) against four common species of ticks affecting dogs in North America
Martin Murphy, Roberto Garcia, Daniela Karadzovska, Daniela Cavalleri, Dan Snyder, Wolfgang Seewald, Theresa Real, Jason Drake, Scott Wiseman and Steve Nanchen

Parasites & Vectors 2017 10:523
Published on: 1 November 2017

> Full Text          > PDF

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