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Diagnostic, molecular and clinical features of COVID-19

- A thematic series on the spectrum of pathological findings in COVID-19

COVID-19 Special issue

In the last few months, the coronavirus disease (COVID-19) has emerged as a worldwide pandemic and is now clearly the most significant global health crisis of our time. COVID-19 continues to present us with major healthcare challenges with over 9 million cases and almost 480,000 deaths around the world and still less than optimal treatment options. The virus initially was identified in Wuhan, Hubei Province, China in 2019 and has rapidly spread across the globe. COVID-19 disease is caused by a novel coronavirus, which has been named “Severe Acute Respiratory Syndrome Corona virus-2 (SARS-CoV-2)”. COVID-19 is highly transmissible among humans and primarily, but not only, affects the lower respiratory tract and lungs.

The editorial team of Diagnostic Pathology is pleased to announce the inauguration of a new thematic series on the pathological spectrum of COVID-19 disease and pathogenesis of SARS-CoV-2. As the editor-in-chief of Diagnostic Pathology, I am especially excited about launching this important series, as it will serve to attract key articles in COVID-19 pathophysiology, diagnostics, molecular pathology and immunology with an emphasis on the clinico-pathological correlation of this disease. The series welcomes submissions on the most up to date understanding of the histopathological features of a SARS-CoV-2 infection including an understanding of the molecular pathology, ultrastructure features of the virus. We are also interested in publishing key articles related to diagnostics of COVID-19 including but not limited to molecular, antigen-based or antibody based assays. As new research on this pathogen transpires every day, we want readers to turn to Diagnostic Pathology for the latest updates and pathological information that will assist researchers and clinical teams to design better diagnostics and therapeutics. We sincerely hope that our readers will find the collection of articles in this series both interesting and useful in disseminating important information relating to the pathology of COVID-19

- Dr. Anil V Parwani, Editor-in Chief, Diagnostic Pathology

  1. Patients with COVID-19 can also have enteric symptoms. Here we analyzed the histopathology of intestinal detachment tissue from a patient with COVID-19.

    Authors: Yanling Feng, Dong Zeng, Lvyin Hu, Yuexiang Yang, Shu Song, Yuhan Shi, Jingjing Xu, Wenjuan Guo, Yun Ling, Tangkai Qi, Qingguo Wu, Feng Li, Jilin Cheng and Hongzhou Lu
    Citation: Diagnostic Pathology 2021 16:40
  2. To date, very few studies on clinical-histopathological correlations of cutaneous disorders associated with COVID-19 have been conducted.

    Authors: Angela Patrì, Maria Vargas, Pasquale Buonanno, Maria Carmela Annunziata, Daniela Russo, Stefania Staibano, Giuseppe Servillo and Gabriella Fabbrocini
    Citation: Diagnostic Pathology 2021 16:16
  3. To explore the clinical characteristics and placental pathological changes of pregnant women with 2019 novel coronavirus (CoV) disease (COVID-19) in the third trimester, and to assess the possibility of vertic...

    Authors: Likun Gao, Jiacai Ren, Li Xu, Xiaokang Ke, Lin Xiong, Xiaoli Tian, Cuifang Fan, Honglin Yan and Jingping Yuan
    Citation: Diagnostic Pathology 2021 16:8
  4. The world is currently witnessing a major devastating pandemic of Coronavirus disease-2019 (COVID-19). This disease is caused by a novel coronavirus named Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-...

    Authors: Sambit K. Mohanty, Abhishek Satapathy, Machita M. Naidu, Sanjay Mukhopadhyay, Shivani Sharma, Lisa M. Barton, Edana Stroberg, Eric J. Duval, Dinesh Pradhan, Alexandar Tzankov and Anil V. Parwani
    Citation: Diagnostic Pathology 2020 15:103
  5. In lung cancer patients infected with COVID-19, pathological features are not easy to distinguish. This report presents detailed histopathological findings in two non-neoplastic subjects whose out-of-hospital ...

    Authors: Roberto Scendoni, Francesca Marchesani, Nunzia Cannovo, Piergiorgio Fedeli and Mariano Cingolani
    Citation: Diagnostic Pathology 2020 15:73