Guest Editors:
Elavarasan Subramani: The University of Texas M.D. Anderson Cancer Center, United States
Marija Trajkovic-Arsic: German Cancer Consortium, Germany
BMC Cancer is calling for submissions to our Collection on metabolism rewiring in cancer.
Elavarasan Subramani: The University of Texas M.D. Anderson Cancer Center, United States
Dr. Subramani is a research investigator at the Department of Cancer Systems Imaging, The UT M.D. Anderson Cancer Center. He has considerable experience in metabolomics, cell, and molecular biological approaches, developing in vitro and in vivo biomarker development and drug discovery models, and defining cancer pathophysiology. He has developed and mechanistically validated robust non-invasive translatable biomarkers that can be used to identify oncogenic events associated with low-grade gliomas and that can be used to monitor response to a broad range of therapies.
Marija Trajkovic-Arsic: German Cancer Consortium, Germany
Dr. Trajkovic-Arsic obtained her Ph.D. in Endocrinology in 2008. Since 2010 she has been active in cancer research focusing on pancreatic ductal adenocarcinoma (PDAC). She is dedicated to deciphering pancreatic cancer's metabolic dependencies and further developing imaging-based approaches for reliable non-invasive detection of PDACs metabolism and its metabolic vulnerabilities. She is mostly known for her research on preclinical mouse models of PDAC and imaging technologies used for addressing PDACs heterogeneity, microenvironment complexity, metabolic activity, and therapy development and evaluation.
BMC Cancer is calling for submissions to our Collection on metabolism rewiring in cancer.
The first observations on metabolic alterations in cancer were made nearly a century ago by Otto Warburg, who discovered the metabolic differences between lactate production of cancer cells and non-malignant tissues. It is now well known that metabolic perturbations are a hallmark of cancer, which allows cancer cells to sustain their uncontrolled proliferation even in a frequently nutrient-poor environment. In the past decade, the field of cancer metabolism has become a topic of renewed interest, unrevealing the impact of metabolic rewiring in the cancer-microenvironment crosstalk and the onset of therapeutic resistance and metastasis.
In recognition of this important field, BMC Cancer has launched this Collection which encourages submissions including but not limited to those addressing:
• Genetic alterations involved in the metabolic reprogramming
• Metabolic alterations within the microenvironment
• Therapeutic approaches targeting cancer metabolism at the cellular or organismal levels
• Metabolites as tumor biomarkers
• Tumor metabolism as a diagnostic tool
• Tumor metabolism and therapy response imaging technologies
• Redox homeostasis in cancer metabolism
• Cancer metabolomics and multi-omics data integration
• Sex-specific metabolic alterations in cancers
• Improving in vitro cancer metabolism studies (new media formulations/conditions)
Image credit: © nobeastsofierce / Stock.adobe.com
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This Collection welcomes the submission of Research Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Cancer metabolism" from the dropdown menu.
Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.
The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.