The next generation sequencing 'problem', namely the generation of huge datasets that are unwieldy for analyses and expensive and problematic to store, has been remedied by the advent of cloud computing, where one rents hardware or storage space. This phenomenon has revolutionized genomic analyses and brought large-scale genomics within reach of smaller labs. The following Genome Biology articles showcase tools and examples of studies that use such technologies.
Sequencing and analysis of an Irish human genome
Recent studies generating complete human sequences from Asian, African and European subgroups have revealed population-specific variation and disease susceptibility loci. Here, choosing a DNA sample from a pop...