Skip to main content


Clinical applications of stem cells

Edited by Mahendra Rao

An article collection in Stem Cell Research & Therapy.

This thematic series focuses on taking stem cells from the lab to the clinic.

This collection of articles has not been sponsored and articles have undergone the journal’s standard peer-review process. The Guest Editor and Editors declare no competing interests.

View all collections published in Stem Cell Research & Therapy

  1. Content type: Review

    Human neural stem cell transplants have potential as therapeutic candidates to treat a vast number of disorders of the central nervous system (CNS). StemCells, Inc. has purified human neural stem cells and dev...

    Authors: Ann Tsukamoto, Nobuko Uchida, Alexandra Capela, Thorsten Gorba and Stephen Huhn

    Citation: Stem Cell Research & Therapy 2013 4:102

    Published on:

  2. Content type: Research

    Intraspinal grafting of human neural stem cells represents a promising approach to promote recovery of function after spinal trauma. Such a treatment may serve to: I) provide trophic support to improve surviva...

    Authors: Sebastiaan van Gorp, Marjolein Leerink, Osamu Kakinohana, Oleksandr Platoshyn, Camila Santucci, Jan Galik, Elbert A Joosten, Marian Hruska-Plochan, Danielle Goldberg, Silvia Marsala, Karl Johe, Joseph D Ciacci and Martin Marsala

    Citation: Stem Cell Research & Therapy 2013 4:57

    Published on:

  3. Content type: Review

    The field of regenerative medicine is approaching translation to clinical practice, and significant safety concerns and knowledge gaps have become clear as clinical practitioners are considering the potential ...

    Authors: John Harding, R Michael Roberts and Oleg Mirochnitchenko

    Citation: Stem Cell Research & Therapy 2013 4:23

    Published on:

  4. Content type: Research

    Adipose tissue is an attractive and abundant source of multipotent stem cells. Human adipose stem cells (ASCs) have shown to have therapeutic relevancy in diverse clinical applications. Nevertheless, expansion...

    Authors: Mimmi Patrikoski, Miia Juntunen, Shayne Boucher, Andrew Campbell, Mohan C Vemuri, Bettina Mannerström and Susanna Miettinen

    Citation: Stem Cell Research & Therapy 2013 4:27

    Published on:

  5. Content type: Review

    Cellular therapy products are an emerging medical product class undergoing rapid scientific and clinical innovation worldwide. These products pose unique regulatory challenges both for countries with existing ...

    Authors: Judith A Arcidiacono, Joan W Blair and Kimberly A Benton

    Citation: Stem Cell Research & Therapy 2012 3:38

    Published on:

  6. Content type: Review

    Therapeutic strategies using stem cells for treating neurological diseases are receiving more attention as the scientific community appreciates cell-autonomous contributions to several diseases of the central ...

    Authors: Akshata A Almad and Nicholas J Maragakis

    Citation: Stem Cell Research & Therapy 2012 3:37

    Published on:

  7. Content type: Editorial

    The remarkable speed with which the field of stem cell biology has evolved is unprecedented and has already changed the way we do science. In this series of articles we have invited leading experts to present ...

    Authors: Mahendra Rao

    Citation: Stem Cell Research & Therapy 2012 3:27

    Published on:

  8. Content type: Review

    Aastrom Biosciences has developed a proprietary cell-processing technology that enables the manufacture of ixmyelocel-T, a patient-specific multicellular therapy expanded from a small sample of a patient's own...

    Authors: Ronnda L Bartel, Caryn Cramer, Kelly Ledford, Amy Longcore, Christopher Parrish, Theresa Stern, Sharon Watling and Frank Zeigler

    Citation: Stem Cell Research & Therapy 2012 3:26

    Published on:

  9. Content type: Review

    Osteoarthritis (OA) is a degenerative disease of the connective tissue and progresses with age in the older population or develops in young athletes following sports-related injury. The articular cartilage is ...

    Authors: Pawan K Gupta, Anjan K Das, Anoop Chullikana and Anish S Majumdar

    Citation: Stem Cell Research & Therapy 2012 3:25

    Published on:

  10. Content type: Review

    Injury and disease of the spinal cord are generally met with a poor prognosis. This poor prognosis is due not only to the characteristics of the diseases but also to our poor ability to deliver therapeutics to...

    Authors: Eleanor M Donnelly, Jason Lamanna and Nicholas M Boulis

    Citation: Stem Cell Research & Therapy 2012 3:24

    Published on: