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Clinical applications of stem cells

Edited by Mahendra Rao

An article collection in Stem Cell Research & Therapy.

This thematic series focuses on taking stem cells from the lab to the clinic.

This collection of articles has not been sponsored and articles have undergone the journal’s standard peer-review process. The Guest Editor and Editors declare no competing interests.

View all collections published in Stem Cell Research & Therapy

  1. Review

    Clinical translation of human neural stem cells

    Human neural stem cell transplants have potential as therapeutic candidates to treat a vast number of disorders of the central nervous system (CNS). StemCells, Inc. has purified human neural stem cells and dev...

    Ann Tsukamoto, Nobuko Uchida, Alexandra Capela, Thorsten Gorba and Stephen Huhn

    Stem Cell Research & Therapy 2013 4:102

    Published on: 29 August 2013

  2. Research

    Amelioration of motor/sensory dysfunction and spasticity in a rat model of acute lumbar spinal cord injury by human neural stem cell transplantation

    Intraspinal grafting of human neural stem cells represents a promising approach to promote recovery of function after spinal trauma. Such a treatment may serve to: I) provide trophic support to improve surviva...

    Sebastiaan van Gorp, Marjolein Leerink, Osamu Kakinohana, Oleksandr Platoshyn, Camila Santucci, Jan Galik, Elbert A Joosten, Marian Hruska-Plochan, Danielle Goldberg, Silvia Marsala, Karl Johe, Joseph D Ciacci and Martin Marsala

    Stem Cell Research & Therapy 2013 4:57

    Published on: 28 May 2013

  3. Review

    Standardization of human stem cell pluripotency using bioinformatics

    The study of cell differentiation, embryonic development, and personalized regenerative medicine are all possible through the use of human stem cells. The propensity for these cells to differentiate into all t...

    Michael W Nestor and Scott A Noggle

    Stem Cell Research & Therapy 2013 4:37

    Published on: 25 April 2013

  4. Review

    Large animal models for stem cell therapy

    The field of regenerative medicine is approaching translation to clinical practice, and significant safety concerns and knowledge gaps have become clear as clinical practitioners are considering the potential ...

    John Harding, R Michael Roberts and Oleg Mirochnitchenko

    Stem Cell Research & Therapy 2013 4:23

    Published on: 28 March 2013

  5. Research

    Development of fully defined xeno-free culture system for the preparation and propagation of cell therapy-compliant human adipose stem cells

    Adipose tissue is an attractive and abundant source of multipotent stem cells. Human adipose stem cells (ASCs) have shown to have therapeutic relevancy in diverse clinical applications. Nevertheless, expansion...

    Mimmi Patrikoski, Miia Juntunen, Shayne Boucher, Andrew Campbell, Mohan C Vemuri, Bettina Mannerström and Susanna Miettinen

    Stem Cell Research & Therapy 2013 4:27

    Published on: 7 March 2013

  6. Review

    Glia: an emerging target for neurological disease therapy

    Therapeutic strategies using stem cells for treating neurological diseases are receiving more attention as the scientific community appreciates cell-autonomous contributions to several diseases of the central ...

    Akshata A Almad and Nicholas J Maragakis

    Stem Cell Research & Therapy 2012 3:37

    Published on: 28 September 2012

  7. Review

    Stem cell therapy for the spinal cord

    Injury and disease of the spinal cord are generally met with a poor prognosis. This poor prognosis is due not only to the characteristics of the diseases but also to our poor ability to deliver therapeutics to...

    Eleanor M Donnelly, Jason Lamanna and Nicholas M Boulis

    Stem Cell Research & Therapy 2012 3:24

    Published on: 9 July 2012

  8. Review

    Mesenchymal stem cells for cartilage repair in osteoarthritis

    Osteoarthritis (OA) is a degenerative disease of the connective tissue and progresses with age in the older population or develops in young athletes following sports-related injury. The articular cartilage is ...

    Pawan K Gupta, Anjan K Das, Anoop Chullikana and Anish S Majumdar

    Stem Cell Research & Therapy 2012 3:25

    Published on: 9 July 2012

  9. Review

    The Aastrom experience

    Aastrom Biosciences has developed a proprietary cell-processing technology that enables the manufacture of ixmyelocel-T, a patient-specific multicellular therapy expanded from a small sample of a patient's own...

    Ronnda L Bartel, Caryn Cramer, Kelly Ledford, Amy Longcore, Christopher Parrish, Theresa Stern, Sharon Watling and Frank Zeigler

    Stem Cell Research & Therapy 2012 3:26

    Published on: 9 July 2012

  10. Editorial

    Stem cells and regenerative medicine

    The remarkable speed with which the field of stem cell biology has evolved is unprecedented and has already changed the way we do science. In this series of articles we have invited leading experts to present ...

    Mahendra Rao

    Stem Cell Research & Therapy 2012 3:27

    Published on: 9 July 2012