Cardiac disease is a significant cause of morbidity and mortality in the canine population worldwide. Various breeds are more susceptible to certain diseases than others and some diseases mirror those found in people. Certain conditions show very high prevalence in particular breeds, with a significant impact on a dog’s longevity and quality of life. Our understanding of these various disease processes has evolved over the past few decades, however, many questions remain unanswered. With the dawn of new genetic and molecular techniques, some of these research questions are slowly being resolved.
Canine Medicine and Genetics invites you to explore this canine cardiology collection. This collection aims to bring together research investigating various and multiple aspects of cardiac diseases in dogs. We hope that this will encourage more research within this complex and fascinating field of canine medicine, and lead to future collaborations between cardiologist clinicians and basic researchers.
Guest edited by Elizabeth Bode (BVSc DipECVIM-CA PhD FHEA FRCVS; University of Liverpool, United Kingdom) and Professor Joanna Dukes-McEwan (BVMS(Hons) MVM PhD DVC DipECVIM-CA(Cardiology) FRCVS RCVS Specialist in Veterinary Cardiology and EBVS® European Specialist in Veterinary Cardiology, University of Liverpool, United Kingdom).
Genetic heterogeneity of the canine angiotensin converting enzyme (ACE) gene is functionally important because the degree of aldosterone breakthrough with ACE-inhibitor therapy is greater in variant positive d...
Subvalvular aortic stenosis (SAS) is one of the most common congenital heart defects of dogs. The disease is characterized by obstruction of the left ventricular outflow tract, resulting in pressure overload ...
Atrial fibrillation (AF) is the most common arrhythmia in dogs. The Irish Wolfhound breed has a high prevalence of AF making them an ideal breed to investigate possible genetic contributions to this disease. T...