Guest Editors: Navdeep Chandel, Matthew Vander Heiden, Karen Vousden, Kathryn Wellen
Cancer cells have unique metabolic and bioenergetic properties, allowing them to thrive in nutrient poor environments and maximize cell growth and proliferation. Myriad inputs feed into the metabolism of cancer and cancer-associated cells; as well as interactions within the tumor microenvironment. Understanding the flexibility of changes in the metabolic program, and the underlying mechanisms, will be key in developing new therapeutic approaches.
The special issue is guest edited by Navdeep Chandel (Northwestern University, USA), Matthew Vander Heiden (Massachusetts Institute of Technology, USA), Karen Vousden (The Francis Crick Institute, UK), and Kathryn Wellen (University of Pennsylvania, USA).
Image adapted from: Bruce Wetzel and Harry Schaefer, National Cancer Institute, National Institutes of Health.