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Cancer cell motility and microenvironment

  1. Content type: Review

    Recent advances in tumor biology led to the realization that, in order to understand the mechanisms involved in proliferation and invasion of tumor cells, an analysis of the complex interactions that tumor cel...

    Authors: Lido Calorini and Francesca Bianchini

    Citation: Cell Communication and Signaling 2010 8:24

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  2. Content type: Review

    Rho GTPases represent a family of small GTP-binding proteins involved in cell cytoskeleton organization, migration, transcription, and proliferation. A common theme of these processes is a dynamic reorganizati...

    Authors: Matteo Parri and Paola Chiarugi

    Citation: Cell Communication and Signaling 2010 8:23

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  3. Content type: Review

    During malignant neoplastic progression the cells undergo genetic and epigenetic cancer-specific alterations that finally lead to a loss of tissue homeostasis and restructuring of the microenvironment. The inv...

    Authors: Jan Brábek, Claudia T Mierke, Daniel Rösel, Pavel Veselý and Ben Fabry

    Citation: Cell Communication and Signaling 2010 8:22

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  4. Content type: Review

    In the genomic era of cancer research, the development of metastases has been attributed to mutations in the tumor that enable the cells to migrate. However, gene analyses revealed that primary tumors and meta...

    Authors: Melanie J Voss and Frank Entschladen

    Citation: Cell Communication and Signaling 2010 8:21

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  5. Content type: Review

    In adult tissue the quiescent state of a single cell is maintained by the steady state conditions of its own microenvironment for what concern both cell-cell as well as cell-ECM interaction and soluble factors...

    Authors: Alina De Donatis, Francesco Ranaldi and Paolo Cirri

    Citation: Cell Communication and Signaling 2010 8:20

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