This collection in Biology of Sex Differences, featuring original research and short review articles, focuses on associative, mechanistic, and translational studies linking pregnancy, pregnancy hypertension, preeclampsia, renal and cardiovascular diseases as they relate to pregnancy outcomes, placental factors, development of hypertension, congenital diseases and adverse fetal outcomes. The editors encourage submission of both basic science research using animal models and clinically relevant translational studies involving human subjects.
Investigation of interleukin-2-mediated changes in blood pressure, fetal growth restriction, and innate immune activation in normal pregnant rats and in a preclinical rat model of preeclampsia
Two important clinical features of preeclampsia (PE) are hypertension and fetal growth restriction. The reduced uterine perfusion pressure (RUPP) preclinical rat model of PE exhibits both of these features. Mo...
Citation: Biology of Sex Differences 2021 12:4