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BMC Medicine Reviews

This list will be updated with all new review articles published in BMC Medicine. All of our articles are open access and therefore free to read and share.

  4. Where should I submit my paper? This is a question that young scientists and trainees frequently ask. In this Commentary, we advise on how to make such a decision whilst balancing the risks and benefits. We ar...

    Authors: Clare Fiala and Eleftherios P. Diamandis
    Citation: BMC Medicine 2019 17:12
    Content type: Mini Review Published on:

  5. Lifestyle factors conferring increased diabetes risk are associated with elevated basal insulin levels (hyperinsulinaemia). The latter predicts later obesity in children and adolescents.

    Authors: Hubert Kolb, Michael Stumvoll, Werner Kramer, Kerstin Kempf and Stephan Martin
    Citation: BMC Medicine 2018 16:232
    Content type: Review Published on:

  6. In real-world clinical practice, the acceptance of anticoagulation therapy in the management of portal vein thrombosis (PVT) in patients with cirrhosis is limited by the fear of an increased bleeding risk. Add...

    Authors: Xingshun Qi, Xiaozhong Guo, Eric M. Yoshida, Nahum Méndez-Sánchez, Valerio De Stefano, Frank Tacke, Andrea Mancuso, Yasuhiko Sugawara, Sien-Sing Yang, Rolf Teschke, Ankur Arora and Dominique-Charles Valla
    Citation: BMC Medicine 2018 16:83
    Content type: Minireview Published on:

  7. Uncertainty about factors influencing the susceptibility and triggers for Graves’ disease persists, along with a wide variation in the response to anti-thyroid drugs, currently at approximately 50% of non-resp...

    Authors: Tristan Struja, Alexander Kutz, Stefan Fischli, Christian Meier, Beat Mueller, Mike Recher and Philipp Schuetz
    Citation: BMC Medicine 2017 15:174
    Content type: Review Published on:

  9. Acute gout arthritis flares contribute dominantly to gout-specific impaired health-related quality of life, representing a progressively increasing public health problem. Flares can be complex and expensive to...

    Authors: Robert Terkeltaub
    Citation: BMC Medicine 2017 15:158
    Content type: Minireview Published on:

  10. Depression remains a debilitating condition with an uncertain aetiology. Recently, attention has been given to the renin–angiotensin system. In the central nervous system, angiotensin II may be important in mu...

    Authors: João Vian, Círia Pereira, Victor Chavarria, Cristiano Köhler, Brendon Stubbs, João Quevedo, Sung-Wan Kim, André F. Carvalho, Michael Berk and Brisa S. Fernandes
    Citation: BMC Medicine 2017 15:144
    Content type: Review Published on:

  16. Over the last decade, there have been major advances in the understanding of the genetic basis of hyperuricaemia and gout as well as of the pharmacogenetics of urate-lowering therapy. Key findings include the ...

    Authors: Nicola Dalbeth, Lisa K. Stamp and Tony R. Merriman
    Citation: BMC Medicine 2017 15:108
    Content type: Minireview Published on:

  17. Calorie restriction (CR) extends lifespan and has been shown to reduce age-related diseases including cancer, diabetes, and cardiovascular and neurodegenerative diseases in experimental models. Recent translat...

    Authors: Ciara H. O’Flanagan, Laura A. Smith, Shannon B. McDonell and Stephen D. Hursting
    Citation: BMC Medicine 2017 15:106
    Content type: Minireview Published on:

  18. Characterizing and monitoring tumor genomes with blood samples could achieve significant improvements in precision medicine. As tumors shed parts of themselves into the circulation, analyses of circulating tum...

    Authors: Samantha Perakis and Michael R. Speicher
    Citation: BMC Medicine 2017 15:75
    Content type: Review Published on:

  19. Chronic hepatitis B virus (HBV) infection is a global public health issue. Although the disease cannot be cured effectively, disease management has been improved over the past decade. The introduction of poten...

    Authors: Tai-Chung Tseng and Jia-Horng Kao
    Citation: BMC Medicine 2017 15:53
    Content type: Minireview Published on:

  21. Immune checkpoint inhibitors have significantly modified the therapeutic landscape of advanced non-small cell lung cancer in second-line settings, with a more recent advancement in first-line settings. Given t...

    Authors: Jordi Remon, Benjamin Besse and Jean-Charles Soria
    Citation: BMC Medicine 2017 15:55
    Content type: Minireview Published on:

    The Erratum to this article has been published in BMC Medicine 2017 15:82

  22. Vascular dementia is a common disorder resulting in considerable morbidity and mortality. Determining the extent to which genes play a role in disease susceptibility and their pathophysiological mechanisms cou...

    Authors: M. Arfan Ikram, Anna Bersano, Raquel Manso-Calderón, Jian-Ping Jia, Helena Schmidt, Lefkos Middleton, Benedetta Nacmias, Saima Siddiqi and Hieab H.H. Adams
    Citation: BMC Medicine 2017 15:48
    Content type: Review Published on:

  23. Non-alcoholic fatty liver disease has emerged a major challenge because of it prevalence, difficulties in diagnosis, complex pathogenesis, and lack of approved therapies. As the burden of hepatitis C abates ov...

    Authors: Brent A. Neuschwander-Tetri
    Citation: BMC Medicine 2017 15:45
    Content type: Minireview Published on:

  25. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common and best known monogenic small vessel disease. Here, we review the clinical, neuroimaging...

    Authors: Ilaria Di Donato, Silvia Bianchi, Nicola De Stefano, Martin Dichgans, Maria Teresa Dotti, Marco Duering, Eric Jouvent, Amos D. Korczyn, Saskia A. J. Lesnik-Oberstein, Alessandro Malandrini, Hugh S. Markus, Leonardo Pantoni, Silvana Penco, Alessandra Rufa, Osman Sinanović, Dragan Stojanov…
    Citation: BMC Medicine 2017 15:41
    Content type: Review Published on:

  27. The vascular contributions to neurodegeneration and neuroinflammation may be assessed by magnetic resonance imaging (MRI) and ultrasonography (US). This review summarises the methodology for these widely avail...

    Authors: Branko Malojcic, Panteleimon Giannakopoulos, Farzaneh A. Sorond, Elsa Azevedo, Marina Diomedi, Janja Pretnar Oblak, Nicola Carraro, Marina Boban, Laszlo Olah, Stephan J. Schreiber, Aleksandra Pavlovic, Zsolt Garami, Nantan M. Bornstein and Bernhard Rosengarten
    Citation: BMC Medicine 2017 15:27
    Content type: Review Published on:

  28. Disease models are useful for prospective studies of pathology, identification of molecular and cellular mechanisms, pre-clinical testing of interventions, and validation of clinical biomarkers. Here, we revie...

    Authors: Atticus H. Hainsworth, Stuart M. Allan, Johannes Boltze, Catriona Cunningham, Chad Farris, Elizabeth Head, Masafumi Ihara, Jeremy D. Isaacs, Raj N. Kalaria, Saskia A. M. J. Lesnik Oberstein, Mark B. Moss, Björn Nitzsche, Gary A. Rosenberg, Julie W. Rutten, Melita Salkovic-Petrisic and Aron M. Troen
    Citation: BMC Medicine 2017 15:16
    Content type: Minireview Published on:

  29. Several controlled clinical studies have evaluated the potential of the infection biomarker procalcitonin (PCT) to improve the diagnostic work-up of patients with bacterial infections and its influence on deci...

    Authors: Ramon Sager, Alexander Kutz, Beat Mueller and Philipp Schuetz
    Citation: BMC Medicine 2017 15:15
    Content type: Minireview Published on:

  30. Post-stroke dementia (PSD) or post-stroke cognitive impairment (PSCI) may affect up to one third of stroke survivors. Various definitions of PSCI and PSD have been described. We propose PSD as a label for any ...

    Authors: Milija D. Mijajlović, Aleksandra Pavlović, Michael Brainin, Wolf-Dieter Heiss, Terence J. Quinn, Hege B. Ihle-Hansen, Dirk M. Hermann, Einor Ben Assayag, Edo Richard, Alexander Thiel, Efrat Kliper, Yong-Il Shin, Yun-Hee Kim, SeongHye Choi, San Jung, Yeong-Bae Lee…
    Citation: BMC Medicine 2017 15:11
    Content type: Review Published on: