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Bioinformatics and systems biology in radiation oncology

Prof Horst Zitzelsberger

  1. Content type: Methodology

    Colony formation assay is the gold standard to determine cell reproductive death after treatment with ionizing radiation, applied for different cell lines or in combination with other treatment modalities. Ass...

    Authors: Herbert Braselmann, Agata Michna, Julia Heß and Kristian Unger

    Citation: Radiation Oncology 2015 10:223

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  2. Content type: Research

    The mitogen-activated protein kinases (MAPK) and the phosphatidylinositol-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) pathways are intertwined on various levels and simultaneous inhibition reduces tum...

    Authors: Sebastian Kuger, Michael Flentje and Cholpon S. Djuzenova

    Citation: Radiation Oncology 2015 10:214

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  3. Content type: Review

    The introduction of next-generation sequencing (NGS) in the field of cancer research has boosted worldwide efforts of genome-wide personalized oncology aiming at identifying predictive biomarkers and novel act...

    Authors: Ingeborg Tinhofer, Franziska Niehr, Robert Konschak, Sandra Liebs, Matthias Munz, Albrecht Stenzinger, Wilko Weichert, Ulrich Keilholz and Volker Budach

    Citation: Radiation Oncology 2015 10:183

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  4. Content type: Research

    Although altered protocols that challenge conventional radiation fractionation have been tested in prospective clinical trials, we still have limited understanding of how to select the most appropriate fractio...

    Authors: Sotiris Prokopiou, Eduardo G. Moros, Jan Poleszczuk, Jimmy Caudell, Javier F. Torres-Roca, Kujtim Latifi, Jae K. Lee, Robert Myerson, Louis B. Harrison and Heiko Enderling

    Citation: Radiation Oncology 2015 10:159

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