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Bioinformatics and systems biology in radiation oncology

Prof Horst Zitzelsberger

  1. Methodology

    CFAssay: statistical analysis of the colony formation assay

    Colony formation assay is the gold standard to determine cell reproductive death after treatment with ionizing radiation, applied for different cell lines or in combination with other treatment modalities. Ass...

    Herbert Braselmann, Agata Michna, Julia Heß and Kristian Unger

    Radiation Oncology 2015 10:223

    Published on: 4 November 2015

  2. Review

    Next-generation sequencing: hype and hope for development of personalized radiation therapy?

    The introduction of next-generation sequencing (NGS) in the field of cancer research has boosted worldwide efforts of genome-wide personalized oncology aiming at identifying predictive biomarkers and novel act...

    Ingeborg Tinhofer, Franziska Niehr, Robert Konschak, Sandra Liebs, Matthias Munz, Albrecht Stenzinger, Wilko Weichert, Ulrich Keilholz and Volker Budach

    Radiation Oncology 2015 10:183

    Published on: 28 August 2015

  3. Research

    A proliferation saturation index to predict radiation response and personalize radiotherapy fractionation

    Although altered protocols that challenge conventional radiation fractionation have been tested in prospective clinical trials, we still have limited understanding of how to select the most appropriate fractio...

    Sotiris Prokopiou, Eduardo G. Moros, Jan Poleszczuk, Jimmy Caudell, Javier F. Torres-Roca, Kujtim Latifi, Jae K. Lee, Robert Myerson, Louis B. Harrison and Heiko Enderling

    Radiation Oncology 2015 10:159

    Published on: 31 July 2015