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Endocrinology and hormone therapy

James N Ingle, V Craig Jordan

  1. Estrogen and its receptor (ER) are critical for development and progression of breast cancer. This pathway is targeted by endocrine therapies that either block ER functions or deplete ER's estrogen ligand. Whi...

    Authors: Rachel Schiff and C Kent Osborne
    Citation: Breast Cancer Research 2005 7:205
    Content type: Review Published on:

  2. Although tamoxifen has been an effective treatment for breast cancer, several novel anti-oestrogen compounds have been developed with a reduced agonist profile on breast and gynaecological tissues. These inclu...

    Authors: Stephen RD Johnston
    Citation: Breast Cancer Research 2005 7:119
    Content type: Review Published on: