Brian Henderson
The development of intervention strategies for carriers of mutations in the BRCA1 and BRCA2 genes has several considerations. The first are primary prevention and secondary prevention in unaffected carriers using...
Citation: Breast Cancer Research 2000 2:283
Risk factors for breast cancer are related to endogenous hormonesand reproductive events. As such, traditional cancer prevention strategies arenot easily applicable. Tamoxifen and other selective estrogen rece...
Citation: Breast Cancer Research 2000 2:277
The potential for a reduction in dietary fat or for an increase in dietary fiber to reduce breast cancer risk has been debated for some years. It is argued here that available research data, even though extens...
Citation: Breast Cancer Research 2000 2:268
The cyclic production of estrogen and progesterone by the premenopausal ovary accounts for the steep rise in breast cancer risk in premenopausal women. These hormones are breast cell mitogens. By reducing expo...
Citation: Breast Cancer Research 2000 2:264
The available results from breast cancer chemoprevention trials are reviewed. Four trials using tamoxifen have been performed, of which three have reported efficacy results. A fifth trial using raloxifene has ...
Citation: Breast Cancer Research 2000 2:258