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Biomaterials for bone and joint

Edited by: Jae Hyup Lee, Seoul National University, College of Medicine, Korea

Bone and joint are the major organs and tissues of the musculoskeletal system. The biomaterials used in bone and joints reconstruct or regenerate the musculoskeletal system and can be used in the field of orthopedic surgery, maxillofacial surgery, dental surgery and neurosurgery. In the meantime, biomaterials in the bone and joint field have developed rapidly, including artificial bone development with osteoinductivity and osteoconductivity, caritilage reconstruction with tissue engineering using stem cells. 
This thematic series in Biomaterials Research covers fabrication, characterization of materials (biomaterials for bone, cartilage, synovium) and applications for biomedical and tissue engineering fields.

To submit a paper to this series, please visit the Biomaterials Research submission site. Make sure to choose the name of the series under the "Are you submitting to a thematic series?" question on the "Additional information" tab.

New articles in the series will appear here as they are published.


  1. In dental or orthopedic surgery, bone substitutes are inserted with implants to promote osteogenesis and enhance osseointegration. The purpose of this research was to evaluate the efficacy of rhBMP-2 (recombin...

    Authors: Hao-Zhen Lyu and Jae Hyup Lee

    Citation: Biomaterials Research 2020 24:5

    Content type: Research article

    Published on:

  2. Delayed bone regeneration of fractures in osteoporosis patients or of critical-size bone defects after tumor resection are a major medical and socio-economic challenge. Therefore, the development of more effec...

    Authors: Jan Krieghoff, Ann-Kristin Picke, Juliane Salbach-Hirsch, Sandra Rother, Christiane Heinemann, Ricardo Bernhardt, Christian Kascholke, Stephanie Möller, Martina Rauner, Matthias Schnabelrauch, Vera Hintze, Dieter Scharnweber, Michaela Schulz-Siegmund, Michael C. Hacker, Lorenz C. Hofbauer and Christine Hofbauer

    Citation: Biomaterials Research 2019 23:26

    Content type: Research article

    Published on:

  3. Collagen-based scaffolds reinforced with hydroxyapatite (HA) are an attractive choice for bone tissue engineering because their composition mimics that of bone. We previously reported the development of compre...

    Authors: Holly E. Weiss-Bilka, Matthew J. Meagher, Joshua A. Gargac, Glen L. Niebur, Ryan K. Roeder and Diane R. Wagner

    Citation: Biomaterials Research 2019 23:15

    Content type: Research article

    Published on:

  4. Bone allografts are used in many orthopedic procedures to provide structural stability as well as an osteoconductive matrix for bone ingrowth and fusion. Traditionally, bone allografts have been preserved by e...

    Authors: Brian Samsell, Davorka Softic, Xiaofei Qin, Julie McLean, Payal Sohoni, Katrina Gonzales and Mark A. Moore

    Citation: Biomaterials Research 2019 23:5

    Content type: Research article

    Published on:

  5. Autologous bone remains the gold standard grafting substrate for bone fusions used for small gaps and critical defects. However, significant morbidity is associated with the harvesting of autologous bone graft...

    Authors: José Miguel Campos, Ana Catarina Sousa, Pedro Olivério Pinto, Jorge Ribeiro, Miguel Lacueva França, Ana Rita Caseiro, Mariana Vieira Branquinho, Sílvia Santos Pedrosa, Carla Mendonça, Ana Brandão, José Domingos Santos, Américo Afonso, Luís Miguel Atayde, Ana Lúcia Luís and Ana Colette Maurício

    Citation: Biomaterials Research 2018 22:38

    Content type: Short report

    Published on:

  6. The chondrogenic differentiation of mesenchymal stem cells (MSCs) is regulated by many factors, including oxygen tensions, growth factors, and cytokines. Evidences have suggested that low oxygen tension seems ...

    Authors: Hyun Cheol Bae, Hee Jung Park, Sun Young Wang, Ha Ru Yang, Myung Chul Lee and Hyuk-Soo Han

    Citation: Biomaterials Research 2018 22:28

    Content type: Research article

    Published on:

    The Correction to this article has been published in Biomaterials Research 2019 23:7