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Biomaterials for bone and joint

Edited by: Jae Hyup Lee, Seoul National University, College of Medicine, Korea

Bone and joint are the major organs and tissues of the musculoskeletal system. The biomaterials used in bone and joints reconstruct or regenerate the musculoskeletal system and can be used in the field of orthopedic surgery, maxillofacial surgery, dental surgery and neurosurgery. In the meantime, biomaterials in the bone and joint field have developed rapidly, including artificial bone development with osteoinductivity and osteoconductivity, caritilage reconstruction with tissue engineering using stem cells. 
This thematic series in Biomaterials Research covers fabrication, characterization of materials (biomaterials for bone, cartilage, synovium) and applications for biomedical and tissue engineering fields. 

  1. Bioceramic β-tricalcium phosphate (β-TCP) is used as a bone-grafting material and a therapeutic drug carrier for treatment of bone defects in the oral and maxillofacial regions due to the osteoconductivity and...

    Authors: Dong Keon Lee, Mi-Ran Ki, Euy Hyun Kim, Chang-Joo Park, Jae Jun Ryu, Hyon Seok Jang, Seung Pil Pack, Yun Kee Jo and Sang Ho Jun
    Citation: Biomaterials Research 2021 25:13
  2. The aim of the study is to characterize a biomedical magnesium alloy and highlighting the loss of mechanical integrity due to the sterilization method. Ideally, when using these alloys is to delay the onset of...

    Authors: Luis Humberto Campos Becerra, Marco Antonio Loudovic Hernández Rodríguez, Raúl Lesso Arroyo, Hugo Esquivel Solís and Alejandro Torres Castro
    Citation: Biomaterials Research 2021 25:9
  3. Biomineralized collagen, consisting of fibrillar type-I collagen with embedded hydroxyapatite mineral, is a bone-mimicking material with potential application as a bone graft substitute. Despite the chemical a...

    Authors: Daniel de Melo Pereira, Matthias Schumacher and Pamela Habibovic
    Citation: Biomaterials Research 2021 25:6
  4. Titanium (Ti) has been utilized as hard tissue replacement owing to its superior mechanical and bioinert property, however, lack in tissue compatibility and biofunctionality has limited its clinical use. Reduc...

    Authors: Moon Sung Kang, Seung Jo Jeong, Seok Hyun Lee, Bongju Kim, Suck Won Hong, Jong Ho Lee and Dong-Wook Han
    Citation: Biomaterials Research 2021 25:4
  5. In dental or orthopedic surgery, bone substitutes are inserted with implants to promote osteogenesis and enhance osseointegration. The purpose of this research was to evaluate the efficacy of rhBMP-2 (recombin...

    Authors: Hao-Zhen Lyu and Jae Hyup Lee
    Citation: Biomaterials Research 2020 24:5
  6. Delayed bone regeneration of fractures in osteoporosis patients or of critical-size bone defects after tumor resection are a major medical and socio-economic challenge. Therefore, the development of more effec...

    Authors: Jan Krieghoff, Ann-Kristin Picke, Juliane Salbach-Hirsch, Sandra Rother, Christiane Heinemann, Ricardo Bernhardt, Christian Kascholke, Stephanie Möller, Martina Rauner, Matthias Schnabelrauch, Vera Hintze, Dieter Scharnweber, Michaela Schulz-Siegmund, Michael C. Hacker, Lorenz C. Hofbauer and Christine Hofbauer
    Citation: Biomaterials Research 2019 23:26
  7. Collagen-based scaffolds reinforced with hydroxyapatite (HA) are an attractive choice for bone tissue engineering because their composition mimics that of bone. We previously reported the development of compre...

    Authors: Holly E. Weiss-Bilka, Matthew J. Meagher, Joshua A. Gargac, Glen L. Niebur, Ryan K. Roeder and Diane R. Wagner
    Citation: Biomaterials Research 2019 23:15
  8. Bone allografts are used in many orthopedic procedures to provide structural stability as well as an osteoconductive matrix for bone ingrowth and fusion. Traditionally, bone allografts have been preserved by e...

    Authors: Brian Samsell, Davorka Softic, Xiaofei Qin, Julie McLean, Payal Sohoni, Katrina Gonzales and Mark A. Moore
    Citation: Biomaterials Research 2019 23:5
  9. Autologous bone remains the gold standard grafting substrate for bone fusions used for small gaps and critical defects. However, significant morbidity is associated with the harvesting of autologous bone graft...

    Authors: José Miguel Campos, Ana Catarina Sousa, Pedro Olivério Pinto, Jorge Ribeiro, Miguel Lacueva França, Ana Rita Caseiro, Mariana Vieira Branquinho, Sílvia Santos Pedrosa, Carla Mendonça, Ana Brandão, José Domingos Santos, Américo Afonso, Luís Miguel Atayde, Ana Lúcia Luís and Ana Colette Maurício
    Citation: Biomaterials Research 2018 22:38
  10. The chondrogenic differentiation of mesenchymal stem cells (MSCs) is regulated by many factors, including oxygen tensions, growth factors, and cytokines. Evidences have suggested that low oxygen tension seems ...

    Authors: Hyun Cheol Bae, Hee Jung Park, Sun Young Wang, Ha Ru Yang, Myung Chul Lee and Hyuk-Soo Han
    Citation: Biomaterials Research 2018 22:28

    The Correction to this article has been published in Biomaterials Research 2019 23:7