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Autophagy Biology: Autophagy and the Cellular Mechanism of Diseases

This series is edited by:

  • Xuehong Xu, Shaanxi Normal University
  • Joseph Bryant, University of Maryland School of Medicine
  • Jianjie Ma, Ohio State University College of Medicine

The series Editors invite you to submit to this article collection entitled “Autophagy Biology: Autophagy and the Cellular Mechanism of Diseases”. The series will be published in Cell & Bioscience.

Autophagy is the natural cellular process of construction and destruction mechanisms involved in physiological development and pathological genesis. From embryogenesis to post-natal development, autophagy (or autophagocytosis) plays a critical role in tissue and organ architecture along with the differentiation of normal tissue and remodelling of pathological advancement. Aiming to expand the therapeutic potential of autophagy, many researchers focus on developing new drugs or treatment strategies for Parkinson's disease, rheumatic diseases and oncogenesis by controlling cell fate via regulating molecular pathways. This series aims to highlight essential molecular and cellular mechanisms for understanding autophagy and its comprehensive associations with cardiac vascular diseases, carcinogenesis, liver diseases, neuronal degeneration and other related disorders. Original research papers and review articles will be considered for publication in this series.  

Topics to be covered include (but are not limited to):

  • Studies focused on fundamental molecular and cellular mechanism of autophagy in biological system;
  • Comprehensive understanding of the function of autophagy in cardiac vascular diseases, liver diseases, neuronal degeneration and other pathological disorders;
  • Drug development against cancers and other autophagy and mitophagy related diseases;
  • Autophagic defense and remodelling of cells and tissues;
  • Animal models on the diseases based on cellular mechanism of autophagy and mitophagy.


  1. Vascular calcification is a closely linked to cardiovascular diseases, such as atherosclerosis, chronic kidney disease, diabetes, hypertension and aging. The extent of vascular calcification is closely correl...

    Authors: Xin Zhou, Sui-Ning Xu, Shu-Tong Yuan, Xinjuan Lei, Xiaoying Sun, Lu Xing, Hui-Jin Li, Chun-Xia He, Wei Qin, Dong Zhao, Peng-Quan Li, Edward Moharomd, Xuehong Xu and Hui-Ling Cao

    Citation: Cell & Bioscience 2021 11:159

    Content type: Review

    Published on:

  2. Neuropeptide Y (NPY), one of the most abundant neuropeptides in the body, is widely expressed in the central and peripheral nervous systems and acts on the cardiovascular, digestive, endocrine, and nervous sys...

    Authors: Yan Zhang, Chu-Yun Liu, Wei-Can Chen, Yan-Chuan Shi, Cong-Mei Wang, Shu Lin and He-Fan He

    Citation: Cell & Bioscience 2021 11:151

    Content type: Review

    Published on:

  3. Autophagy is required for oogenesis and plays a critical role in response to aging caused by oxidative stress. However, there have been no reports on regulation of cytoprotective autophagy in female germline s...

    Authors: Xiaoyan Yuan, Geng. G. Tian, Xiuying Pei, Xiaopeng Hu and Ji Wu

    Citation: Cell & Bioscience 2021 11:107

    Content type: Research

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  4. Autophagy is a prominent mechanism to preserve homeostasis and the response to intracellular or extracellular stress. Autophagic degradation can be selectively targeted to dysfunctional subcellular compartment...

    Authors: Qi Wu, Xin Yu, Le Liu, Shengrong Sun and Si Sun

    Citation: Cell & Bioscience 2021 11:49

    Content type: Review

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  5. Autophagy has a crucial role in the defense against parasites. The interplay existing between host autophagy and parasites has varied outcomes due to the kind of host cell and microorganism. The presence of au...

    Authors: George Ghartey-Kwansah, Frank Adu-Nti, Benjamin Aboagye, Amandus Ankobil, Edward Eyipe Essuman, Yeboah Kwaku Opoku, Samuel Abokyi, Emmanuel Kwasi Abu and Johnson Nyarko Boampong

    Citation: Cell & Bioscience 2020 10:101

    Content type: Review

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  6. Ischemic stroke poses a severe risk to human health worldwide, and currently, clinical therapies for the disease are limited. Delta opioid receptor (DOR)-mediated neuroprotective effects against ischemia have ...

    Authors: Zelin Lai, Lingling Gu, Lu Yu, Huifen Chen, Zhenhua Yu, Cheng Zhang, Xiaoqing Xu, Mutian Zhang, Min Zhang, Mingliang Ma, Zheng Zhao and Jun Zhang

    Citation: Cell & Bioscience 2020 10:79

    Content type: Research

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  7. Eukaryotic cells demonstrate two tightly linked vesicular transport systems, comprising intracellular vesicle transport and extracellular vesicle transport system. Intracellular transport vesicles can transloc...

    Authors: Leila Salimi, Ali Akbari, Nassrollah Jabbari, Behnam Mojarad, Ali Vahhabi, Sławomir Szafert, Sadegh Asghari Kalashani, Hamid Soraya, Muhammad Nawaz and Jafar Rezaie

    Citation: Cell & Bioscience 2020 10:64

    Content type: Review

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  8. In the past 30 years, incidences of non-alcoholic fatty liver disease (NAFLD) has risen by 30%. However, there is still no clear mechanism or accurate method of anticipating liver failure. Here we reveal the p...

    Authors: Liyang Wang, MengMeng Xu, Odell D. Jones, Zhongguang Li, Yu Liang, Qiuxia Yu, Jiali Li, Yajun Wu, Xinjuan Lei, Boling He, Huimin Yue, Liqin Xiao, Rong Zhou, Wei Zhang, Xin Zhou, Yuhui Zhang…

    Citation: Cell & Bioscience 2020 10:55

    Content type: Research

    Published on: