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Asthma: Towards a Cure

Guest Editor:

Professor Reynold Panettieri, Jr, MD, Rutgers Institute for Translational Medicine and Science, Rutgers University, United States of America

Submission Status: Open   |   Submission Deadline: 31 May 2025


Respiratory Research is calling for submissions to our collection on Asthma: Towards a Cure. The collection seeks manuscripts that address cutting-edge science addressing the unmet need to manage and cure asthma. Such manuscripts could include novel biomarkers that predict therapeutic responses to novel or current therapy. 

Image credit: © yodiyim / Getty Images / iStock

About the collection

Respiratory Research is calling for submissions to our collection on Asthma: Towards a Cure. The collection seeks manuscripts that address cutting-edge science addressing the unmet need to manage and cure asthma. Such manuscripts could include novel biomarkers that predict therapeutic responses to novel or current therapy. Fundamental, translational, and clinical studies are encouraged that can promote the dissemination and implementation of novel approaches to change clinical practice and policy.

  1. Asthma, a prevalent chronic inflammatory disorder, is shaped by a multifaceted interplay between genetic susceptibilities and environmental exposures. Despite strides in deciphering its pathophysiological land...

    Authors: Dihui Zhang, Xiaowei Pu, Man Zheng, Guanghui Li and Jia Chen
    Citation: Respiratory Research 2024 25:327
    Content type: Research Published on:

  2. Tea polyphenols (TPs), prominent constituents of green tea, possess remarkable antioxidant and anti-inflammatory properties. However, their therapeutic potential is limited due to low absorption and poor bioav...

    Authors: Suidong Ouyang, Peishan Lu, Jianing Li, Hua Jin, Wanhua Wu, Renxing Luo, Bin Wang, Xueqin Huang, Xinlong Lian and Gonghua Huang
    Citation: Respiratory Research 2024 25:311
    Content type: Research Published on:

  4. In recent years, the incorporation of LAMAs into asthma therapy has been expected to enhance symptom control. However, a significant number of patients with asthma continue to experience poorly managed symptom...

    Authors: Hiroyuki Sugawara, Atsushi Saito, Saori Yokoyama and Hirofumi Chiba
    Citation: Respiratory Research 2024 25:300
    Content type: Research Published on:

  5. Shortening of airway smooth muscle and bronchoconstriction are pathognomonic for asthma. Airway shortening occurs through calcium-dependent activation of myosin light chain kinase, and RhoA-dependent calcium s...

    Authors: Elizabeth L. McDuffie, Reynold A. Panettieri Jr. and Charles P. Scott
    Citation: Respiratory Research 2024 25:295
    Content type: Review Published on:

  6. Extracellular traps (ETs) are a specialized form of innate immune defense in which leukocytes release ETs composed of chromatin and active proteins to eliminate pathogenic microorganisms. In addition to the an...

    Authors: Wei Gu, Chunli Huang, Gongqi Chen, Weiqiang Kong, Lu Zhao, Huiru Jie and Guohua Zhen
    Citation: Respiratory Research 2024 25:290
    Content type: Review Published on:

  7. Obesity is associated with airway hyperresponsiveness and lung fibrosis, which may reduce the effectiveness of standard asthma treatment in individuals suffering from both conditions. Statins and proprotein co...

    Authors: Lin Liang, Sook In Chung, Tae-Eun Guon, Kyung Hee Park, Jae-Hyun Lee and Jung-Won Park
    Citation: Respiratory Research 2024 25:213
    Content type: Research Published on:

  8. Asthma stands as one of the most prevalent chronic respiratory conditions in children, with its pathogenesis tied to the actived antigen presentation by dendritic cells (DCs) and the imbalance within T cell su...

    Authors: JinYing Xiang, Bo Liu, Yan Li, Yinying Ren, Yuehan Li, Mi Zhou, Jinyue Yu, Zhengxiu Luo, Enmei Liu, Zhou Fu and Fengxia Ding
    Citation: Respiratory Research 2024 25:182
    Content type: Research Published on:

  9. Severe asthma is associated with an increased risk for exacerbations, reduced lung function, fixed airflow obstruction, and substantial morbidity and mortality. The concept of remission in severe asthma as a n...

    Authors: Inês Farinha and Liam G Heaney
    Citation: Respiratory Research 2024 25:178
    Content type: Review Published on:

  10. In chronic pulmonary diseases characterized by inflammation and airway obstruction, such as asthma and COPD, there are unmet needs for improved treatment. Quinolines is a group of small heterocyclic compounds ...

    Authors: Jesper Bergwik, Jielu Liu, Médea Padra, Ravi K. V. Bhongir, Lloyd Tanner, Yujiao Xiang, Mia Lundblad, Arne Egesten and Mikael Adner
    Citation: Respiratory Research 2024 25:146
    Content type: Research Published on:

  11. DEHP, a common plasticizer known for its hormone-disrupting properties, has been associated with asthma. However, a significant proportion of adult asthma cases are “non-atopic”, lacking a clear etiology.

    Authors: Yuan-Ting Hsu, Chao-Chien Wu, Chin-Chou Wang, Chau-Chyun Sheu, Yi-Hsin Yang, Ming-Yen Cheng, Ruay-Sheng Lai, Sum-Yee Leung, Chi-Cheng Lin, Yu-Feng Wei, Yung-Fa Lai, Meng-Hsuan Cheng, Huang-Chi Chen, Chih-Jen Yang, Chien-Jen Wang, Huei-Ju Liu…
    Citation: Respiratory Research 2024 25:139
    Content type: Research Published on:

  12. Allergic diseases exert a considerable impact on global health, thus necessitating investigations into their etiology and pathophysiology for devising effective prevention and treatment strategies. This study ...

    Authors: Junhao Tu, Jinyang Wen, Qing Luo, Xin Li, Deyun Wang and Jing Ye
    Citation: Respiratory Research 2024 25:94
    Content type: Research Published on:

  13. Asthma is a heterogeneous disease characterized by airway inflammation and remodeling, whose pathogenetic complexity was associated with abnormal responses of various cell types in the lung. The specific inter...

    Authors: Xiu Yu, Lifei Li, Bicheng Cai, Wei Zhang, Quan Liu, Nan Li, Xing Shi, Li Yu, Rongchang Chen and Chen Qiu
    Citation: Respiratory Research 2024 25:76
    Content type: Research Published on:

  15. Airway remodeling is a poorly reversible feature of asthma which lacks effective therapeutic interventions. CD147 can regulate extracellular matrix (ECM) remodeling and tissue fibrosis, and participate in the ...

    Authors: Zhao Li, Tao Cheng, Yaning Guo, Rong Gao, Xuankun Ma, Xuecong Mao and Xinpeng Han
    Citation: Respiratory Research 2024 25:6
    Content type: Research Published on:

  16. Allergic asthma is a common respiratory disease that significantly impacts human health. Through in silico analysis of human lung RNASeq, we found that asthmatic lungs display lower levels of Isthmin-1 (ISM1) ...

    Authors: Jong Huat Tee, Udhaya Vijayakumar, Mahalakshmi Shanmugasundaram, Terence Y. W. Lam, Wupeng Liao, Yuansheng Yang, W. S. Fred Wong and Ruowen Ge
    Citation: Respiratory Research 2023 24:269
    Content type: Research Published on:

  17. Rhinovirus infections commonly evoke asthma exacerbations in children and adults. Recurrent asthma exacerbations are associated with injury-repair responses in the airways that collectively contribute to airwa...

    Authors: Cassandra Spector, Camden M. De Sanctis, Reynold A. Panettieri Jr. and Cynthia J. Koziol-White
    Citation: Respiratory Research 2023 24:238
    Content type: Review Published on:

  18. Asthma is a common, chronic inflammatory disease of the airways that affects millions of people worldwide and is associated with significant healthcare costs. Eosinophils, a type of immune cell, play a critica...

    Authors: Kunlu Shen, Mengyuan Zhang, Ruiheng Zhao, Yun Li, Chunxiao Li, Xin Hou, Bingqing Sun, Bowen Liu, Min Xiang and Jiangtao Lin
    Citation: Respiratory Research 2023 24:231
    Content type: Review Published on:

  19. Accumulating clinical evidence links Obstructive Sleep Apnea (OSA) with worse outcomes of asthma, but impact on airway function remains sparsely studied. We tested effects of Chronic Intermittent Hypoxia (CIH)...

    Authors: Mihaela Teodorescu, Ruolin Song, Jacqueline A. Brinkman and Ronald L. Sorkness
    Citation: Respiratory Research 2023 24:189
    Content type: Correspondence Published on:

  20. It has previously been shown that the Helicobacter pylori (H. pylori)-derived molecule vacuolating cytotoxin A (VacA) could be suitable for the treatment of allergic airway disease. The therapeutic activity of th...

    Authors: Jonas Raspe, Mona S. Schmitz, Kimberly Barbet, Georgia C. Caso, Timothy L. Cover, Anne Müller, Christian Taube and Sebastian Reuter
    Citation: Respiratory Research 2023 24:178
    Content type: Research Published on:

Submission Guidelines

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This Collection welcomes submission of Research Articles, Data Notes, Case Reports, Study Protocols, and Database Articles. Before submitting your manuscript, please ensure you have read our submission guidelines. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Asthma: Towards a Cure" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Guest Editor has no competing interests with the submissions which he will handle through the peer review process. The peer review of any submissions for which the Guest Editor has competing interests is handled by another Editorial Board Member who has no competing interests.