Fibroblast biology

George Kollias

Fibroblast biology Effector signals released by the synovial fibroblast in arthritis

There is mounting evidence indicating that the synovial fibroblast is a direct effector of tissue injury and matrix remodeling in inflammatory synovitis. Through the elaboration of effector signals including c...

Authors: Christopher Ritchlin

Citation: Arthritis Research & Therapy 2000 2:356

Content type: Review Published on: 23 June 2000
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Fibroblast biology: Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis

There is growing evidence that activated synovial fibroblasts, as part of a complex cellular network, play an important role in the pathogenesis of rheumatoid arthritis. In recent years, significant progress h...

Authors: Thomas Pap, Ulf Müller-Ladner, Renate E Gay and Steffen Gay

Citation: Arthritis Research & Therapy 2000 2:361

Content type: Review Published on: 8 June 2000
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Fibroblast biology Signals targeting the synovial fibroblast in arthritis

Fibroblast-like cells in the synovial lining (type B lining cells), stroma and pannus tissue are targeted by many signals, such as the following: ligands binding to cell surface receptors; lipid soluble, small...

Authors: Yrjö T Konttinen, Tian-Fang Li, Mika Hukkanen, Jian Ma, Jing-Wen Xu and Ismo Virtanen

Citation: Arthritis Research & Therapy 2000 2:348

Content type: Review Published on: 8 June 2000
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Fibroblast biology Development and differentiation of synovial fibroblasts in arthritis

Synovial fibroblasts occur as two phenotypes - intimal and subintimal. The specialised intimal phenotype includes expression of uridine diphosphoglucose dehydrogenase (UDPGD), vascular cell adhesion molecule-1...

Authors: Jonathan CW Edwards

Citation: Arthritis Research & Therapy 2000 2:344

Content type: Review Published on: 8 June 2000
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Fibroblast biology Synovial fibroblasts in rheumatoid arthritis: leading role or chorus line?

Authors: Dimitris Kontoyiannis and George Kollias

Citation: Arthritis Research & Therapy 2000 2:342

Content type: Review Published on: 8 June 2000
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Fibroblast biology

Fibroblast biology Effector signals released by the synovial fibroblast in arthritis

Fibroblast biology: Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis

Fibroblast biology Signals targeting the synovial fibroblast in arthritis

Fibroblast biology Development and differentiation of synovial fibroblasts in arthritis

Fibroblast biology Synovial fibroblasts in rheumatoid arthritis: leading role or chorus line?