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Ageing, autoimmunity and arthritis


  1. Review

    Ageing, autoimmunity and arthritis: Perturbations of TCR signal transduction pathways with ageing – a biochemical paradigm for the ageing immune system

    It is widely accepted that cell-mediated immune functions decline with age, rendering an individual more susceptible to infection and possibly cancer, as well as to age-associated autoimmune diseases. The exac...

    Tamàs Fülöp Jr, Anis Larbi, Gilles Dupuis and Graham Pawelec

    Arthritis Res Ther 2003 5:290

    Published on: 16 October 2003