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Antimicrobial resistance: present scenario and future developments

Increasing bacterial resistance to antibiotics is a critical problem worldwide, with many health organisations making the issue a priority for future development and research. Whilst there is a desperate need for new effective antimicrobials to be developed, it is also important to understand the mechanisms and epidemiology of the resistant pathogens currently present in the community. This collection of articles published in Annals of Clinical Microbiology and Antimicrobials ​​​​​​​showcases the latest research and review articles investigating the current state of antimicrobial resistance worldwide, along with those which examine potential future developments. If you would like your manuscript to be considered for this collection, please indicate so at the time of submission.

View all collections published in Annals of Clinical Microbiology and Antimicrobials.

  1. To determine the incidence, risk factors, and impact on outcome of prolonged empirical antifungal treatment in ICU patients.

    Authors: Mohamed Zein, Erika Parmentier-Decrucq, Amer Kalaoun, Olivier Bouton, Frédéric Wallyn, Anne Baranzelli, Dia Elmanser, Boualem Sendid and Saad Nseir
    Citation: Annals of Clinical Microbiology and Antimicrobials 2014 13:11
  2. The consumption of carbapenems has increased worldwide, together with the increase in resistant gram negative bacilli. Subsequently, the prevalence of carbapenem-resistant Acinetobacter infections has increased r...

    Authors: Aziz Ogutlu, Ertugrul Guclu, Oguz Karabay, Aylin Calica Utku, Nazan Tuna and Mehmet Yahyaoglu
    Citation: Annals of Clinical Microbiology and Antimicrobials 2014 13:7
  3. Multi-drug resistant coagulaso-negative staphylococci (CNS) have become an increasing problem in nosocomial infections connected with the presence of medical devices. The paper aimed to analyze the prevalence ...

    Authors: Monika Brzychczy-Wloch, Maria Borszewska-Kornacka, Ewa Gulczynska, Jadwiga Wojkowska-Mach, Malgorzata Sulik, Monika Grzebyk, Malgorzata Luchter, Piotr B Heczko and Malgorzata Bulanda
    Citation: Annals of Clinical Microbiology and Antimicrobials 2013 12:41
  4. A review of the published and unpublished literature on bacterial resistance in human and animals was performed. Sixty-eight articles/reports from the Democratic Republic of Congo (DRC), Mozambique, Tanzania a...

    Authors: Stephen E Mshana, Mecky Matee and Mark Rweyemamu
    Citation: Annals of Clinical Microbiology and Antimicrobials 2013 12:28
  5. Bacterial resistance to antibiotics is growing up day by day in both community and hospital setting, with a significant impact on the mortality and morbidity rates and the financial burden that is associated. ...

    Authors: Matteo Bassetti, Maria Merelli, Chiara Temperoni and Augusta Astilean
    Citation: Annals of Clinical Microbiology and Antimicrobials 2013 12:22
  6. The presence of clinical Acinetobacter baumannii (A. baumannii) isolates with differing antibiotic resistance phenotypes in the same patient causes difficulties and confusion in treatment. This phenomenon may be ...

    Authors: Chang-Hua Chen and Chieh-Chen Huang
    Citation: Annals of Clinical Microbiology and Antimicrobials 2013 12:21
  7. Resistance rates to polymyxin B in surveillance studies have been very low despite its increasing use worldwide as the last resort therapy for multidrug-resistant Gram-negative bacilli. However, two other resi...

    Authors: Juliana Barin, Andreza Francisco Martins, Bianca Lucia Heineck, Afonso Luis Barth and Alexandre Prehn Zavascki
    Citation: Annals of Clinical Microbiology and Antimicrobials 2013 12:15
  8. Shigella flexneri serotype 1c emerged as a critical isolate from children in Egypt and Pakistan. The pattern of antimicrobial susceptibility (AMS) and resistance genes of this serotype have yet to be characterize...

    Authors: Salwa F Ahmed, John Klena, Tupur Husain, Jesse Monestersky, Amel Naguib and Momtaz O Wasfy
    Citation: Annals of Clinical Microbiology and Antimicrobials 2013 12:9
  9. Urinary tract infections (UTIs) are one of the most common bacterial infections with global expansion. These infections are predominantly caused by uropathogenic Escherichia coli (UPEC).

    Authors: Hassan Momtaz, Azam Karimian, Mahboobeh Madani, Farhad Safarpoor Dehkordi, Reza Ranjbar, Meysam Sarshar and Negar Souod
    Citation: Annals of Clinical Microbiology and Antimicrobials 2013 12:8
  10. Antibiotic combination therapy for Helicobacter pylori eradication must be adapted to local resistance patterns, but the epidemiology of H. pylori resistance to antibiotics is poorly documented in Africa. The aim...

    Authors: Abdoulaye Seck, Christophe Burucoa, Daouda Dia, Mouhamadou Mbengue, Manuella Onambele, Josette Raymond and Sebastien Breurec
    Citation: Annals of Clinical Microbiology and Antimicrobials 2013 12:3
  11. Quarter milk samples from cows were examined to determine the prevalence of Staphylococcus aureus (SA) and different antibiotic resistant pattern were determined in a cross-sectional study design.

    Authors: Deresse Daka, Solomon G/silassie and Dawit Yihdego
    Citation: Annals of Clinical Microbiology and Antimicrobials 2012 11:26
  12. Increased infection caused by multidrug resistant (MDR) Pseudomonas aeruginosa has raised awareness of the resistance situation worldwide. Carbapenem resistance among MDR (CR-MDR) P. aeruginosa has become a serio...

    Authors: Piyatip Khuntayaporn, Preecha Montakantikul, Piroon Mootsikapun, Visanu Thamlikitkul and Mullika Traidej Chomnawang
    Citation: Annals of Clinical Microbiology and Antimicrobials 2012 11:25
  13. Brucellosis poses a significant public health problem in Mediterranean countries, including Egypt. Treatment of this disease is often empirical due to limited information on the antibiotic susceptibility profi...

    Authors: Mohamed Abdel-Maksoud, Brent House, Momtaz Wasfy, Bassem Abdel-Rahman, Guillermo Pimentel, Gehan Roushdy and Erica Dueger
    Citation: Annals of Clinical Microbiology and Antimicrobials 2012 11:24
  14. The presence of resistant bacteria in the oral cavity can be the major cause of dental antibiotic prophylaxis failure. Multidrug efflux has been described for many organisms, including bacteria and fungi as pa...

    Authors: Bochra Kouidhi, Tarek Zmantar, Hanene Jrah, Yosra Souiden, Kamel Chaieb, Kacem Mahdouani and Amina Bakhrouf
    Citation: Annals of Clinical Microbiology and Antimicrobials 2011 10:29
  15. Urinary tract infections (UTIs) remain the common infections diagnosed in outpatients as well as hospitalized patients. Current knowledge on antimicrobial susceptibility pattern is essential for appropriate th...

    Authors: Mohammed Akram, Mohammed Shahid and Asad U Khan
    Citation: Annals of Clinical Microbiology and Antimicrobials 2007 6:4
  16. Pseudomonas aeruginosa is the third most common pathogen responsible for nosocomial infections and the prevalence of multiple resistant isolates has been increasing. Ninety-nine clinical isolates were studied in ...

    Authors: Serap Gençer, Öznur Ak, Nur Benzonana, Ayşe Batırel and Serdar Özer
    Citation: Annals of Clinical Microbiology and Antimicrobials 2002 1:2