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10 Years of Alzheimer's Research & Therapy

New Content ItemAlzheimer’s Research & Therapy is proud to mark ten years since its launch in 2009. 

Over the last decade, the journal has established itself as the major forum for translational research into Alzheimer’s Disease, other forms of Dementia, and neurodegenerative disease.

The research published in Alzheimer’s Research & Therapy has not only shaped the journal in its founding ten years, but also continues to drive the direction of the wider field. 

In celebration of this milestone, we are launching a thematic series on emerging themes in Alzheimer's research such as blood biomarkers, sex-specific differences and novel treatment approaches. This series is open to submissions from authors across the research community.

We will also be collating new reviews on advances in the field across the last decade, impactful research from the journal’s archives, and an Editorial reflecting on the journal’s progress since its foundations. 

Submissions to this series are now closed. All published manuscripts have been subject to the journal's standard peer review process.

  1. Soluble beta-amyloid (Aβ) can be cleared from the brain through various mechanisms including enzymatic degradation, glial cell phagocytosis, transport across the blood-brain barrier, and glymphatic clearance. ...

    Authors: Weixi Feng, Yanli Zhang, Ze Wang, Hanrong Xu, Ting Wu, Charles Marshall, Junying Gao and Ming Xiao
    Citation: Alzheimer's Research & Therapy 2020 12:125
  2. Quantifying changes in the levels of biological and cognitive markers prior to the clinical presentation of Alzheimer’s disease (AD) will provide a template for understanding the underlying aetiology of the cl...

    Authors: Christoforos Hadjichrysanthou, Stephanie Evans, Sumali Bajaj, Loizos C. Siakallis, Kevin McRae-McKee, Frank de Wolf and Roy M. Anderson
    Citation: Alzheimer's Research & Therapy 2020 12:74
  3. Alzheimer's disease (AD) is frequently accompanied by sleep impairment, which can induce AD-related neurodegeneration. We herein investigated the sleep architecture, cognition, and cerebrospinal fluid (CSF) bi...

    Authors: Claudio Liguori, Fabio Placidi, Francesca Izzi, Matteo Spanetta, Nicola Biagio Mercuri and Alessandra Di Pucchio
    Citation: Alzheimer's Research & Therapy 2020 12:5

    The Correction to this article has been published in Alzheimer's Research & Therapy 2020 12:53

  4. The global impact of Alzheimer’s disease (AD) continues to increase, and focused efforts are needed to address this immense public health challenge. National leaders have set a goal to prevent or effectively t...

    Authors: Jeffrey Cummings, Paul S. Aisen, Bruno DuBois, Lutz Frölich, Clifford R. Jack Jr, Roy W. Jones, John C. Morris, Joel Raskin, Sherie A. Dowsett and Philip Scheltens
    Citation: Alzheimer's Research & Therapy 2016 8:39
  5. Current projections of the scale of the coming dementia epidemic assume that the age- and sex-specific prevalence of dementia will not vary over time, and that population ageing alone (increasing the number of...

    Authors: Martin Prince, Gemma-Claire Ali, Maëlenn Guerchet, A. Matthew Prina, Emiliano Albanese and Yu-Tzu Wu
    Citation: Alzheimer's Research & Therapy 2016 8:23
  6. There is a growing body of evidence that subtle deficits in instrumental activities of daily living (IADL) may be present in mild cognitive impairment (MCI). However, it is not clear if there are IADL domains ...

    Authors: Katrin Jekel, Marinella Damian, Carina Wattmo, Lucrezia Hausner, Roger Bullock, Peter J Connelly, Bruno Dubois, Maria Eriksdotter, Michael Ewers, Elmar Graessel, Milica G Kramberger, Emma Law, Patrizia Mecocci, José L Molinuevo, Louise Nygård, Marcel GM Olde-Rikkert…
    Citation: Alzheimer's Research & Therapy 2015 7:17
  7. Autosomal-dominant Alzheimer's disease has provided significant understanding of the pathophysiology of Alzheimer's disease. The present review summarizes clinical, pathological, imaging, biochemical, and mole...

    Authors: Randall J Bateman, Paul S Aisen, Bart De Strooper, Nick C Fox, Cynthia A Lemere, John M Ringman, Stephen Salloway, Reisa A Sperling, Manfred Windisch and Chengjie Xiong
    Citation: Alzheimer's Research & Therapy 2011 3:1
  8. Recently, it has become clear that head trauma can lead to a progressive neurodegeneration known as chronic traumatic encephalopathy. Although the medical literature also implicates head trauma as a risk facto...

    Authors: Brandon E Gavett, Robert A Stern, Robert C Cantu, Christopher J Nowinski and Ann C McKee
    Citation: Alzheimer's Research & Therapy 2010 2:18