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Advances in neuroimaging: Insights into neurological and psychiatric disease

BioMedical Engineering OnLine articles edited by Peipeng Liang, Kelvin Wong & Defeng Wang

© Leng et al.; licensee BioMed Central. 2015Over the last decade, major advances in neuroimaging have provided new opportunities to study the pathophysiological mechanisms of neurological and psychiatric diseases. Emerging techniques also have the potential to be tremendously useful in clinical research and neuroscience. This cross-journal series will focus on the advancement of computational and experimental studies that examine the abnormalities (functional or structural, static or dynamic) of neurological and psychiatric disorders, based on neuroimaging data.

By bringing together research published in BioMed Central journals, we aim to present an overview  of state-of-the-art advances in neuroimaging and to highlight their numerous applications within clinical medicine and neuroscience.

This series is now accepting submissions, please see the participating journals on the right for further information.

This collection of articles has not been sponsored and articles have undergone the journal’s standard peer-review process. The Guest Editors declare no competing interests.

  1. Content type: Research

    Arterial spin labeling (ASL) provides a noninvasive way to measure cerebral blood flow (CBF). The CBF estimation from ASL is heavily contaminated by noise and the partial volume (PV) effect. The multiple measu...

    Authors: Yang Liu, Ze Wang, Ruihua Liang, Zhengrong Liang and Hongbing Lu

    Citation: BioMedical Engineering OnLine 2019 18:12

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  2. Content type: Review Article

    Neuroinflammation is primarily characterized by overexpression of proinflammatory mediators produced by glial activation or immune cell infiltration. Several kinases have been shown to be critical mediators in...

    Authors: Chong Ning, Hui-Min David Wang, Rong Gao, Yu-Chia Chang, Fengqing Hu, Xianjun Meng and Shi-Ying Huang

    Citation: BioMedical Engineering OnLine 2018 17:46

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  3. Content type: Research article

    Striatal atrophy is detectable many years before the predicted onset of motor symptoms in premanifest Huntington’s disease (HD). However, the extent of these neurodegenerative changes at the actual time of con...

    Authors: Emma M. Coppen, Jeroen van der Grond and Raymund A. C. Roos

    Citation: Journal of Clinical Movement Disorders 2018 5:2

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  4. Content type: Research

    Hippocampal atrophy is a supportive feature for the diagnosis of probable Alzheimer’s disease (AD). However, even for an expert neuroradiologist, tracing the hippocampus and measuring its volume is a time cons...

    Authors: Nicola Amoroso, Marianna La Rocca, Roberto Bellotti, Annarita Fanizzi, Alfonso Monaco and Sabina Tangaro

    Citation: BioMedical Engineering OnLine 2018 17:6

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  5. Content type: Review

    Chorea is a hyperkinetic movement disorder consisting of involuntary irregular, flowing movements of the trunk, neck or face. Although Huntington’s disease is the most common cause of chorea in adults, chorea ...

    Authors: Debra J. Ehrlich and Ruth H. Walker

    Citation: Journal of Clinical Movement Disorders 2017 4:8

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  6. Content type: Research

    In schizophrenia, executive dysfunction is the most critical cognitive impairment, and is associated with abnormal neural activities, especially in the frontal lobes. Complexity estimation using electroencepha...

    Authors: Yi Yu, Yun Zhao, Yajing Si, Qiongqiong Ren, Wu Ren, Changqin Jing and Hongxing Zhang

    Citation: BioMedical Engineering OnLine 2016 15:131

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  7. Content type: Research

    Microelectrode array (MEA) is a widely used technique to study for example the functional properties of neuronal networks derived from human embryonic stem cells (hESC-NN). With hESC-NN, we can investigate the...

    Authors: Kerstin Lenk, Barbara Priwitzer, Laura Ylä-Outinen, Lukas H. B. Tietz, Susanna Narkilahti and Jari A. K. Hyttinen

    Citation: BioMedical Engineering OnLine 2016 15:105

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  8. Content type: Research

    The objective of this study is to assess standardized histograms of signal intensities of T1 signal and T2 signal on sagittal view without enhancement during (1) acute stage, and (2) convalescence stage of ped...

    Authors: Hongwu Zeng, Wenxian Huang, Feiqiu Wen, Yonker Wang, Yungen Gan, Weibin Zeng, Ranran Chen, Yanxia He, Zaiyi Liu, Changhong Liang and Kelvin K. L. Wong

    Citation: BioMedical Engineering OnLine 2016 15:25

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  9. Content type: Research

    Double injection of blood into cisterna magna using a rabbit model results in cerebral vasospasm. An unacceptably high mortality rate tends to limit the application of model. Ultrasound guided puncture can pro...

    Authors: Yongchao Chen, Youzhi Zhu, Yu Zhang, Zixuan Zhang, Juan Lian, Fucheng Luo, Xuefei Deng and Kelvin KL Wong

    Citation: BioMedical Engineering OnLine 2016 15:19

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  10. Content type: Research article

    The role of 3DTOF MRA in the follow up (FU) of coiled cerebral aneurysms is well established. Though CEMRA (Contrast Enhanced Magnetic Resonance Angiography) has demonstrated to be superior to 3DTOF MRA in sho...

    Authors: Nicoletta Anzalone, C. De Filippis, F. Scomazzoni, G. Calori, A. Iadanza, F. Simionato and C. Righi

    Citation: Neurovascular Imaging 2015 1:11

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  11. Content type: Research article

    In symptomatic intracranial atherosclerotic stenosis (ICAS), its hemodynamic impact may affect the risk of stroke recurrence, in addition to the degree of luminal stenosis. We therefore conducted a pilot study...

    Authors: Xinyi Leng, Fabien Scalzo, Albert K Fong, Mark Johnson, Hing Lung Ip, Yannie Soo, Thomas Leung, Liping Liu, Edward Feldmann, Ka Sing Wong and David S Liebeskind

    Citation: Neurovascular Imaging 2015 1:1

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  12. Content type: Research

    Intensity normalization is an important preprocessing step in brain magnetic resonance image (MRI) analysis. During MR image acquisition, different scanners or parameters would be used for scanning different s...

    Authors: Xiaofei Sun, Lin Shi, Yishan Luo, Wei Yang, Hongpeng Li, Peipeng Liang, Kuncheng Li, Vincent C T Mok, Winnie C W Chu and Defeng Wang

    Citation: BioMedical Engineering OnLine 2015 14:73

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  13. Content type: Research article

    The value of noninvasive assessment of carotid plaque composition in identifying patients with high coronary risk remains elusive. We sought to determine whether and which carotid plaque components are associa...

    Authors: Jie Sun, Daniel S. Hippe, Hunter R. Underhill, Baocheng Chu, Tobias Saam, Norihide Takaya, Jianming Cai, Minako Oikawa-Wakayama, Wei Yu, Li Dong, Chun Yuan and Thomas S. Hatsukami

    Citation: Neurovascular Imaging 2015 1:5

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