Claude Chelala, PhD, Deputy Centre Lead, Centre for Cancer Biomarkers and Biotherapeutics, Barts Cancer Institute (BCI), Queen Mary University of London (QMUL), UK
Claude Chelala joined the Barts Cancer Institute to translate her work from a substantial basic/computational research platform into a translational/patient setting. She established an interdisciplinary team with expertise in translational bioinformatics, health data science, molecular biology, biobanking and software engineering.
She leads the Health Informatics and Bioinformatics for the Pancreatic Cancer Research Fund Tissue Bank and the Breast Cancer Now Tissue Bank creating an ecosystem with interlinking clinical, in vivo, in vitro and in silico resources. Her research focuses on breast cancer recurrence and the clinical utility of histologically normal tissue adjacent to the tumor and imaging free text reports. She uses liquid biopsy, omics and health records for tracking tumor dynamics in pancreatic cancer where quality of life and survival are especially poor. She has developed translational tools such as SNPnexus to prioritize clinically relevant sequence variations for precision medicine as well as translational platforms / analytics hubs for integrating omics data for skin aging, pancreatic cancer and breast cancer.
Pasquale Pisapia, MD, PhD, Department of Public Health, University of Naples Federico II, Naples, Italy
Pasquale Pisapia, MD, PhD, is Assistant Professor, Specialist in Anatomic Pathology at the University of Naples Federico II in Naples, Italy. His main research interest is in molecular pathology, with a particular focus on the development, validation, and implementation of molecular techniques, especially NGS, in molecular predictive and prognostic biomarkers in different solid tumors (for example, NSCLC and CRC), on both tissue (histological or cytological) and liquid biopsy specimens.
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