Biology of recently discovered cytokines

John O'Shea

Biology of recently discovered cytokines: Interleukin-17 – a unique inflammatory cytokine with roles in bone biology and arthritis

IL-17 and its receptor are founding members of an emerging family of cytokines and receptors with many unique characteristics. IL-17 is produced primarily by T cells, particularly those of the memory compartme...

Authors: Sarah L Gaffen

Citation: Arthritis Res Ther 2004 6:240

Content type: Review Published on: 8 October 2004
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Biology of recently discovered cytokines: Discerning the pro- and anti-inflammatory properties of interleukin-27

IL-27 is a recently identified heterodimeric cytokine produced in response to microbial and host derived inflammatory cues. Initial studies indicated that IL-27 promotes the generation of Th1 responses require...

Authors: Alejandro V Villarino and Christopher A Hunter

Citation: Arthritis Res Ther 2004 6:225

Content type: Review Published on: 16 August 2004
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