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Trauma-induced coagulopathy and critical bleeding

Edited by Professor Shigeki Kushimoto

This thematic series was published in Journal of Intensive Care

Hemorrhage is the most important contributing factor of acute-phase mortality in trauma patients. During the last 10 years, there has been a dramatic evolution in our understanding of trauma-induced coagulopathy. For example, trauma itself and traumatic shock-induced endogenous coagulopathy are both referred to as acute traumatic coagulopathy (ATC) and multifactorial trauma-associated coagulation impairment. Alongside these understandings, a widespread paradigm shift in the resuscitation of critically injured patients has been observed. Understanding the pathophysiology of trauma-induced coagulopathy and novel therapeutic strategies are therefore vitally important issues for the management of patients with severe trauma.

  1. Content type: Review

    Achieving a balance between organ perfusion and hemostasis is critical for optimal fluid resuscitation in patients with severe trauma. The concept of “permissive hypotension” refers to managing trauma patients...

    Authors: Daisuke Kudo, Yoshitaro Yoshida and Shigeki Kushimoto

    Citation: Journal of Intensive Care 2017 5:11

    Published on:

  2. Content type: Review

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    Authors: Takeshi Nishida, Takahiro Kinoshita and Kazuma Yamakawa

    Citation: Journal of Intensive Care 2017 5:5

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  3. Content type: Review

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    Authors: Mineji Hayakawa

    Citation: Journal of Intensive Care 2017 5:3

    Published on:

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