Skip to main content

Current Evidence and Future Directions in the Treatment of Colorectal Cancer

Page 1 of 2

  1. The inflammatory biomarker “C-reactive protein to albumin ratio (CAR)” has been reported to significantly correlate to a variety of human cancers. However, there are conflicting results regarding the prognosti...

    Authors: Chun-Kai Liao, Yen-Lin Yu, Yueh-Chen Lin, Yu-Jen Hsu, Yih-Jong Chern, Jy-Ming Chiang and Jeng-Fu You

    Citation: World Journal of Surgical Oncology 2021 19:139

    Content type: Review

    Published on:

  2. Radiotherapy is a main therapeutic method for cancers, including colon cancer. In the current study, we aim to explore the effects of circular RNA (circRNA) circ_0055625 in the progression and radiosensitivity...

    Authors: Chao Gao, Yi Zhang, Yanming Tian, Chun Han, Lan Wang, Boyue Ding, Hua Tian, Chaoxi Zhou, Yingchao Ju, Ale Peng and Qiyao Yu

    Citation: World Journal of Surgical Oncology 2021 19:131

    Content type: Research

    Published on:

  3. Most previous studies compared survival between left-sided and right-sided colon cancer without adjustment for clinicopathological parameters. We investigated the effect of sidedness on survival among patients...

    Authors: Zhuang-Sheng Huang, Jun-Wei Wu, Ying Li, Yu-Hai Lin and Xu-Yuan Li

    Citation: World Journal of Surgical Oncology 2021 19:127

    Content type: Research

    Published on:

  4. Lymphovascular invasion (LVI) is defined as the presence of cancer cells in lymphatics or blood vessels. This study aimed to evaluate the prognostic value of LVI in stage II colorectal cancer (CRC) patients wi...

    Authors: Zhenyan Gao, Huihua Cao, Xiang Xu, Qing Wang, Yugang Wu and Qicheng Lu

    Citation: World Journal of Surgical Oncology 2021 19:125

    Content type: Research

    Published on:

  5. The Chinese Society of Clinical Oncology guidelines 2018 and the recent update of that (version 2020) recommends accurate examination before major treatment for decision(s) in cases of colon cancer. Also, the ...

    Authors: Yadong Zhou, Zhiwei Han, Fafu Dou and Tao Yan

    Citation: World Journal of Surgical Oncology 2021 19:120

    Content type: Research

    Published on:

  7. Radical resection is associated with good prognosis among patients with cT1/T2Nx rectal cancer. However, still some of the patients experienced cancer recurrence following radical resection. This study tried t...

    Authors: I-Li Lai, Jeng-Fu You, Yih-Jong Chern, Wen-Sy Tsai, Jy-Ming Chiang, Pao-Shiu Hsieh, Hsin-Yuan Hung and Yu-Jen Hsu

    Citation: World Journal of Surgical Oncology 2021 19:116

    Content type: Research

    Published on:

  9. Colon cancer is a commonly worldwide cancer with high morbidity and mortality. Long non-coding RNAs (lncRNAs) are involved in many biological processes and are closely related to the occurrence of colon cancer...

    Authors: Meihong Gao, Yang Guo, Yifu Xiao and Xuequn Shang

    Citation: World Journal of Surgical Oncology 2021 19:104

    Content type: Research

    Published on:

  10. Hepatectomy for resectable colorectal liver metastasis (CRLM) is recommended. However, the efficacy of upfront hepatectomy without neoadjuvant chemotherapy (NAC) is unclear due to the uncertainty of perioperat...

    Authors: Kosuke Ono, Tomoyuki Abe, Akihiko Oshita, Yusuke Sumi, Takuya Yano, Hiroshi Okuda, Manabu Kurayoshi, Tsuyoshi Kobayashi, Hideki Ohdan, Toshio Noriyuki and Masahiro Nakahara

    Citation: World Journal of Surgical Oncology 2021 19:97

    Content type: Research

    Published on:

  11. Colorectal cancer is the third most common type of cancer in the world. We characterize a cohort of patients who survived up to 5 years without recurrence and identify factors predicting the probability of cure.

    Authors: Inge van den Berg, Robert R. J. Coebergh van den Braak, Jeroen L. A. van Vugt, Jan N. M. Ijzermans and Stefan Buettner

    Citation: World Journal of Surgical Oncology 2021 19:96

    Content type: Research

    Published on:

  12. Lymph node metastasis is a major prognostic sign of colorectal carcinoma and an important indicator for individualized treatment. M2 macrophages play a key role in carcinogenesis and tumor development by enhan...

    Authors: Yanping Wang, Jikun Wang, Chunyu Yang, Yue Wang, Jinhao Liu, Zuoxiu Shi, Yanlei Chen, Yang Feng, Xueqian Ma and Shifeng Qiao

    Citation: World Journal of Surgical Oncology 2021 19:91

    Content type: Research

    Published on:

  15. This study aimed to investigate the short-term and oncological impact of the Endoscopic Surgical Skill Qualification System (ESSQS) by the Japan Society for Endoscopic Surgery on the operator performing laparo...

    Authors: Keisuke Kazama, Masakatsu Numata, Toru Aoyama, Yosuke Atsumi, Hiroshi Tamagawa, Teni Godai, Hiroyuki Saeki, Yusuke Saigusa, Manabu Shiozawa, Norio Yukawa, Munetaka Masuda and Yasushi Rino

    Citation: World Journal of Surgical Oncology 2021 19:53

    Content type: Research

    Published on:

  16. Circular RNAs (circRNAs) are a class of endogenous single-strand RNA transcripts with crucial regulation in human cancers. The objective of this study is to investigate the role of circ_0082182 in CRC and its ...

    Authors: Ruijie Liu, Ping Deng, Yonglian Zhang, Yonglan Wang and Cuiping Peng

    Citation: World Journal of Surgical Oncology 2021 19:51

    Content type: Research

    Published on:

  17. Histopathology is a crucial part of diagnosis and treatment guidance of colorectal cancer. In Denmark, it is not routine to biopsy during self-expandable metallic stent (SEMS) placement as a treatment option f...

    Authors: Sigrid Skov Bennedsgaard and Lene Hjerrild Iversen

    Citation: World Journal of Surgical Oncology 2021 19:48

    Content type: Review

    Published on:

  18. Robotic and laparoscopic surgery for rectal cancer has been applied in the clinic for decades; nevertheless, which surgical approach has a lower rate of postoperative complications is still inconclusive. There...

    Authors: Bo Tang, Xiong Lei, Junhua Ai, Zhixiang Huang, Jun Shi and Taiyuan Li

    Citation: World Journal of Surgical Oncology 2021 19:38

    Content type: Research

    Published on:

  19. The clinical significance of the geriatric nutritional risk index (GNRI) in locally advanced rectal cancer (LARC) patients undergoing preoperative chemoradiotherapy (CRT) followed by curative surgery has not b...

    Authors: Shozo Ide, Yoshinaga Okugawa, Yusuke Omura, Akira Yamamoto, Takashi Ichikawa, Takahito Kitajima, Tadanobu Shimura, Hiroki Imaoka, Hiroyuki Fujikawa, Hiromi Yasuda, Takeshi Yokoe, Yoshiki Okita, Masaki Ohi and Yuji Toiyama

    Citation: World Journal of Surgical Oncology 2021 19:34

    Content type: Research

    Published on:

  20. Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) improves survival in selected patients with peritoneal metastasis (PM) from colorectal cancer (CRC). However, little ...

    Authors: Yasuyuki Kamada, Koya Hida, Haruaki Ishibashi, Shouzou Sako, Akiyoshi Mizumoto, Masumi Ichinose, Naveen Padmanabhan, Shinya Yoshida and Yutaka Yonemura

    Citation: World Journal of Surgical Oncology 2021 19:31

    Content type: Research

    Published on:

  21. Colorectal cancer patients undergoing surgical resection are at increased short-term risk of post-operative adverse events. However, specific predictors for long-term major adverse cardiac and cerebrovascular ...

    Authors: Chieh Yang Koo, Bee-Choo Tai, Dedrick Kok Hong Chan, Li Ling Tan, Ker Kan Tan and Chi-Hang Lee

    Citation: World Journal of Surgical Oncology 2021 19:21

    Content type: Research

    Published on:

  22. Colorectal anastomosis using the double stapling technique (DST) has become a standard procedure. However, DST is difficult to perform in patients with anal stenosis because a circular stapler cannot be insert...

    Authors: Yosuke Tajima, Tsunekazu Hanai, Hidetoshi Katsuno, Koji Masumori, Yoshikazu Koide, Keigo Ashida, Hiroshi Matsuoka, Junichiro Hiro, Tomoyoshi Endo, Tadahiro Kamiya, Yongchol Chong, Kotaro Maeda and Ichiro Uyama

    Citation: World Journal of Surgical Oncology 2021 19:14

    Content type: Case report

    Published on:

  23. Colon cancer is a worldwide leading cause of cancer-related mortality, and the prognosis of colon cancer is still needed to be improved. This study aimed to construct a prognostic model for predicting the prog...

    Authors: Zhengyu Fang, Sumei Xu, Yiwen Xie and Wenxi Yan

    Citation: World Journal of Surgical Oncology 2021 19:13

    Content type: Research

    Published on:

  25. Though better short-term outcomes were frequently reported, differences in specimen parameters and the rate of subsequent peritoneal recurrence between intracorporeal anastomosis (IA) and extracorporeal anasto...

    Authors: Chun-Kai Liao, Yih-Jong Chern, Yueh-Chen Lin, Yu-Jen Hsu, Jy-Ming Chiang, Wen-Sy Tsai, Pao-Shiu Hsieh, Hsin-Yuan Hung, Chien-Yuh Yeh and Jeng-Fu You

    Citation: World Journal of Surgical Oncology 2021 19:6

    Content type: Research

    Published on:

  26. Heterotopic ossification (HO) is the formation of osseous tissue outside the skeleton. HO in malignant tumors of the digestive tract is extremely rare, as is ossification in metastatic lesions from HO-negative...

    Authors: Hideki Nagano, Tamotsu Togawa, Takeshi Watanabe, Kenji Ohnishi, Toshihisa Kimura, Atsushi Iida, Sakon Noriki, Yoshiaki Imamura, Yasunori Sato and Takanori Goi

    Citation: World Journal of Surgical Oncology 2021 19:2

    Content type: Case report

    Published on:

  27. Minimally invasive liver surgery (MILS) in the treatment of colorectal liver metastases (CRLM) is increasing in incidence. The aim of this work was to present our experience by reporting short-term and long-te...

    Authors: Mirhasan Rahimli, Aristotelis Perrakis, Vera Schellerer, Andrew Gumbs, Eric Lorenz, Mareike Franz, Jörg Arend, Victor-Radu Negrini and Roland Siegfried Croner

    Citation: World Journal of Surgical Oncology 2020 18:333

    Content type: Research

    Published on:

  28. The alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase (ALKBH2) gene is involved in DNA repair and is expressed in different types of malignancies. However, the role of ALKBH2 in colorectal carcinoma (C...

    Authors: Bingxin Ke, Kejun Ye and Shaobing Cheng

    Citation: World Journal of Surgical Oncology 2020 18:328

    Content type: Research

    Published on:

  29. Colorectal cancer (CRC) is the most common tumor of the gastrointestinal tract. Anastomotic leak (AL) and prolonged postoperative ileus (PPOI) are two important complications of colorectal surgery. In this obs...

    Authors: Michele Ammendola, Michele Ruggiero, Carlo Talarico, Riccardo Memeo, Giorgio Ammerata, Antonella Capomolla, Rosalinda Filippo, Roberto Romano, Socrate Pallio, Giuseppe Navarra, Severino Montemurro and Giuseppe Currò

    Citation: World Journal of Surgical Oncology 2020 18:327

    Content type: Research

    Published on:

  30. Esophageal cancer patients often feel depressed and are fearful of metastasis and death. The objective of this study was to clarify the characteristics of patients with psychological distress at all 5 time poi...

    Authors: Yu Ohkura, Junichi Shindoh, Kanako Ichikura, Harushi Udagawa, Masaki Ueno and Eisuke Matsushima

    Citation: World Journal of Surgical Oncology 2020 18:326

    Content type: Research

    Published on:

  31. Fluoropyrimidines and platinum are still widely used for colorectal cancer (CRC) management. Several studies have reported that mutations of dihydropyrimidine dehydrogenase (DPYD) and glutathione S-transferase pi...

    Authors: Xunwei Deng, Jingyuan Hou, Qiaoting Deng and Zhixiong Zhong

    Citation: World Journal of Surgical Oncology 2020 18:321

    Content type: Research

    Published on:

  32. The rate of pulmonary metastasectomy from colorectal cancer (CRC) has increased with recent advances in chemotherapy, diagnostic techniques, and surgical procedures. The purpose of this study was to investigat...

    Authors: Masahiro Fukada, Nobuhisa Matsuhashi, Takao Takahashi, Yoshihiro Tanaka, Naoki Okumura, Hirotaka Yamamoto, Koyo Shirahashi, Hisashi Iwata, Kiyoshi Doi and Kazuhiro Yoshida

    Citation: World Journal of Surgical Oncology 2020 18:314

    Content type: Research

    Published on:

  33. Nonoperative management after neoadjuvant treatment in low rectal cancer enables organ preservation and avoids surgical morbidity. Our aim is to compare oncological outcomes in patients with clinical complete ...

    Authors: Mariana F. Coraglio, Martin A. Eleta, Mirta R. Kujaruk, Javier H. Oviedo, Enrique L. Roca, Guillermo A. Masciangioli, Guillermo Mendez and Ilma S. Iseas

    Citation: World Journal of Surgical Oncology 2020 18:313

    Content type: Research

    Published on:

  34. The impact of lateral lymph node dissection (LLND) in locally advanced lower rectal cancer remains controversial. This study is to compare total mesorectal excision (TME) with or without LLND in lower rectal c...

    Authors: Xiang Gao, Cun Wang, Yongyang Yu, Dujanand Singh, Lie Yang and Zongguang Zhou

    Citation: World Journal of Surgical Oncology 2020 18:304

    Content type: Research

    Published on:

  35. Laparoscopic surgery for T4 colon cancer may be safe in selected patients. We hypothesized that small tumor size might preoperatively predict a good laparoscopic surgery outcome. Herein, we compared the clinic...

    Authors: Sung Sil Park, Joon Sang Lee, Hyoung-Chul Park, Sung Chan Park, Dae Kyung Sohn, Jae Hwan Oh, Kyung Su Han, Dong-Won Lee, Dong-Eun Lee, Sung-Bum Kang, Kyu Joo Park and Seung-Yong Jeong

    Citation: World Journal of Surgical Oncology 2020 18:299

    Content type: Research

    Published on:

  37. Colorectal cancer (CRC) poses a heavy threat to human health owing to its high incidence and mortality. Circular RNAs (circRNAs) were investigated to participate in the progression of CRC, whereas there was no...

    Authors: Yanhe Liu, Hui Li, Xiaoyi Ye, Anlong Ji, Xiangwei Fu, Haishan Wu and Xiangyong Zeng

    Citation: World Journal of Surgical Oncology 2020 18:255

    Content type: Research

    Published on:

  38. It has been demonstrated that simultaneous resection of both primary colorectal lesion and metastatic hepatic lesion is a safe approach with low mortality and postoperative complication rates. However, there a...

    Authors: Long Pan, Chenhao Tong, Siyuan Fu, Jing Fang, Qiuxia Gu, Shufeng Wang, Zhiyu Jiang, Sarun Juengpanich and Xiujun Cai

    Citation: World Journal of Surgical Oncology 2020 18:251

    Content type: Research

    Published on:

  40. Natural orifice specimen extraction surgery is a novel technique of minimally invasive surgery. The purpose of this study was to compare the safety of laparoscopic anterior resection with natural orifice speci...

    Authors: Jun He, Hai-Bo Yao, Chang-Jian Wang, Qin-Yan Yang, Jian-Ming Qiu, Jin-Ming Chen, Zhong Shen and Guan-Gen Yang

    Citation: World Journal of Surgical Oncology 2020 18:215

    Content type: Research

    Published on:

  41. Laparoscopic tumor-specific mesorectal excision (TSME) preserving the left colic artery and superior rectal artery is still a technically challenging procedure. We conducted this study to demonstrate the feasi...

    Authors: Chi Zhang, Hao-tang Wei, Wenqing Hu, Yueming Sun, Qinyuan Zhang, Masanobu Abe, Zhuoran Du, Yingying Xu, Liang Zong and Xiang Hu

    Citation: World Journal of Surgical Oncology 2020 18:212

    Content type: Research

    Published on:

  42. One of the most severe complications of low anterior rectal resection is anastomotic leakage (AL). The creation of a loop ileostomy (LI) reduces the prevalence of AL requiring surgical intervention. However, u...

    Authors: Marcin Zeman, Marek Czarnecki, Andrzej Chmielarz, Adam Idasiak, Maciej Grajek and Agnieszka Czarniecka

    Citation: World Journal of Surgical Oncology 2020 18:207

    Content type: Research

    Published on:

  43. To assess the feasibility and short-term outcomes of neoadjuvant chemoradiotherapy (CCRT) followed by transanal total mesorectal excision assisted by single-port laparoscopic surgery (TaTME-SPLS) for low-lying...

    Authors: Yen-Jung Lu, Chien-Hsin Chen, En-Kwang Lin and Szu-Yuan Wu

    Citation: World Journal of Surgical Oncology 2020 18:198

    Content type: Research

    Published on:

  44. Colorectal cancer resection surgery with transvaginal specimen extraction is becoming increasingly accepted and used by surgeons. However, few publications on robotic anterior sigmoid colon and rectal cancer r...

    Authors: Gengmei Gao, Lan Chen, Rui Luo, Bo Tang and Taiyuan Li

    Citation: World Journal of Surgical Oncology 2020 18:190

    Content type: Research

    Published on:

  45. To evaluate the feasibility and safety of a new surgical method, complete laparoscopic extended right hemicolectomy with preservation of the ileocecal junction in right-transverse colon cancer.

    Authors: Hao Su, Hongliang Wu, Bing Mu, Mandula Bao, Shou Luo, Chuanduo Zhao, Qian Liu, Xishan Wang, Zhixiang Zhou and Haitao Zhou

    Citation: World Journal of Surgical Oncology 2020 18:159

    Content type: Research

    Published on:

  46. The purpose of this study was to compare clinicopathological features of patients with non-schistosomal and schistosomal colorectal cancer to explore the effect of schistosomiasis on colorectal cancer (CRC) pa...

    Authors: Weixia Wang, Kui Lu, Limei Wang, Hongyan Jing, Weiyu Pan, Sinian Huang, Yanchao Xu, Dacheng Bu, Meihong Cheng, Jing Liu, Jican Liu, Weidong Shen, Yingyi Zhang, Junxia Yao and Ting Zhu

    Citation: World Journal of Surgical Oncology 2020 18:149

    Content type: Research

    Published on:

  47. The GOD VISION wireless smart glass-shaped monitor (INBYTE) was used in the treatment of an elderly patient with mixed breathing disorder undergoing transanal minimally invasive surgery (TAMIS) for low rectal ...

    Authors: Nobuhisa Matsuhashi, Yoshinori Iwata, Mana Kawajiri, Takao Takahashi, Shigeru Kiyama, Shunya Kiriyama, Machi Uehara, Takeharu Imai, Hisashi Imai, Yoshihiro Tanaka, Naoki Okumura and Kazuhiro Yoshida

    Citation: World Journal of Surgical Oncology 2020 18:141

    Content type: Case report

    Published on:

  48. Colorectal cancer (CRC) is an important current problem concerning public health due to its high incidence and mortality. Advances in molecular and cellular knowledge and the detection of new disease biomarker...

    Authors: Ana Nogués, Eunate Gallardo-Vara, Mª. Paz Zafra, Paloma Mate, Jose Luis Marijuan, Alfredo Alonso, Luisa Mª. Botella and Mª. Isabel Prieto

    Citation: World Journal of Surgical Oncology 2020 18:99

    Content type: Research

    Published on:

  49. Whether primary tumor location of colorectal cancer (CRC) affects survival of patients after resection of liver metastases remains controversial. This study was conducted to investigate the differences in clin...

    Authors: Yuanping Zhang, Yongjin Wang, Yichuan Yuan, Jiliang Qiu, Yuxiong Qiu, Wei He, Yun Zheng, Zhiqiang Wang, Yangkui Gu, Zhenhai Lu, Gong Chen, Peirong Ding, Xiaojun Wu, Zhizhong Pan, Desen Wan, Yuhong Li…

    Citation: World Journal of Surgical Oncology 2020 18:98

    Content type: Research

    Published on:

  50. Mini-invasive colorectal cancer surgery was adopted widely in recent years. This meta-analysis aimed to compare hand-assisted laparoscopic surgery (HALS) with open right hemicolectomy (OS) for malignant disease.

    Authors: Mohamed Ali Chaouch, Mohamed Wejih Dougaz, Meriem Mesbehi, Hichem Jerraya, Ramzi Nouira, Jim S. Khan and Chadli Dziri

    Citation: World Journal of Surgical Oncology 2020 18:91

    Content type: Review

    Published on: