Laura McCulloch: University of Edinburgh, UK
Andrew Greenhalgh: University of Manchester, UK
Submission Status: Open | Submission Deadline: 31 October 2023
Journal of Inflammation is calling for submissions to our collection on Testing the boundaries of the brain’s immune system. The central nervous system is immunologically unique with specialised immune cells residing within its tissue and across its borders. In recent years, our understanding of the interaction of the CNS-associated immune system and the CNS parenchyma has improved and various specialized regions, including the meninges and the glymphatics, play crucial roles in mediating neuroinflammation during disease and injury.
Image: Defence at the brain’s borders: CD11b+ F4/80+ meningeal perivascular macrophages lining vessels showing their heterogeneity in expression of MHCII-blue; CD169-green; CD163-red (Hyperion imaging, Greenhalgh Lab, unpublished data)