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Sjögren's syndrome

Thomas Dörner

  1. Content type: Review

    The difficulty in predicting the consequences of interactions between different cytokine networks has increased with the expansion of the T helper (Th) cell universe and the discovery of numerous B lymphocyte-...

    Authors: Pierre Youinou and Jacques-Olivier Pers

    Citation: Arthritis Research & Therapy 2011 13:227

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  2. Content type: Review

    Sjögren's syndrome (SS), a systemic autoimmune disease, is characterized by inflammation of exocrine tissues accompanied by a significant loss of their secretory function. Clinical symptoms develop late and th...

    Authors: Nicolas Delaleu, Cuong Q Nguyen, Ammon B Peck and Roland Jonsson

    Citation: Arthritis Research & Therapy 2011 13:217

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  3. Content type: Review

    Previously, a dominant role of the adaptive immune system in the pathogenesis of Sjögren's syndrome was suspected. Recent advances, however, have revealed a major role of the type I IFN pathway, documented by ...

    Authors: Hui Zhi Low and Torsten Witte

    Citation: Arthritis Research & Therapy 2011 13:218

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  4. Content type: Review

    Circumstantial evidence suggests that retroviruses play a role in the pathogenesis of Sjögren's syndrome. Such evidence, derived from studies of patients with Sjögren's syndrome, includes the following: the pr...

    Authors: Nikolaos V Sipsas, Maria N Gamaletsou and Haralampos M Moutsopoulos

    Citation: Arthritis Research & Therapy 2011 13:212

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  5. Content type: Review

    In vitro and in vivo experimental data have pointed to new immunopathogenic mechanisms in primary Sjögren's syndrome (pSS). The availability of targeted treatment modalities has opened new ways to selectively tar...

    Authors: Cees GM Kallenberg, Arjan Vissink, Frans GM Kroese, Wayel H Abdulahad and Hendrika Bootsma

    Citation: Arthritis Research & Therapy 2011 13:205

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