Edited by: Sadanori Akita, Rajeev B. Ahuja
Scar contracture after traumatic injury can result in severe functional problems, pain and issues with esthetics. In joint areas, it often leads to limited range of motion, deformity and even disability, which is especially true in pediatric patients.The most powerful treatment option for contracture release and reconstruction is by surgical procedures, in which skin grafts and flaps have been successfully used, although it is still unclear which procedure is most effective. Furthermore, achieving a balance between scar resurfacing and minimizing donor site morbidity is a challenging problem that depends on the size of the area involved, the region of involvement, and the availability of the non scarred tissue for use as skin flaps.
This thematic collection covers recent understanding in molecular pathogenesis of burn scar contracture, surgical treatment methods and innovative strategies including growth factor, and stem cell therapies in management of scar contracture.