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Stromal cells and progenitor cells for osteoarticular regeneration

Edited by:
Christian Jorgensen, MD, PhD, University of Montpellier, France 

Submission Status: Closed

This collection is no longer accepting submissions.


Stem Cell Research & Therapy is calling for submissions to our collection on Stromal cells and progenitor cells for osteoarticular regeneration. Mesenchymal stem cells (MSCs) is an attractive therapy since these cells exhibit chondrogenic and anti-inflammatory properties. Mesenchymal cells have regenerative capacity of cartilage, protective tissue hypoxia and suffering, prevention of fibrosis and reduction of local inflammatory process.

This Collection supports and amplifies research related to SDG 3.

Image credit: Christian Jorgensen

  1. Human adipose-derived stem cells (ADSCs) exert a strong anti-inflammatory effect, and synovium-derived stem cells (SDSCs) have high chondrogenic potential. Thus, this study aims to investigate whether a combin...

    Authors: Jianqun Wu, Songqiang Huang, Yangyi Yu, Qiang Lian, Yang Liu, Wenfeng Dai, Qisong Liu, Yonghao Pan, Gui-ang Liu, Kai Li, Chao Liu and Guangheng Li
    Citation: Stem Cell Research & Therapy 2024 15:261
    Content type: Research Published on:

About the collection

Stem Cell Research & Therapy is calling for submissions to our collection on Stromal cells and progenitor cells for osteoarticular regeneration. Mesenchymal stem cells (MSCs) is an attractive therapy since these cells exhibit chondrogenic and anti-inflammatory properties. Mesenchymal cells have regenerative capacity of cartilage, protective tissue hypoxia and suffering, prevention of fibrosis and reduction of local inflammatory process. MSCs are isolated from a large number of tissues, including bone marrow, and adipose tissues. They are able to differentiate into mesodermal lineages (osteoblasts, chondrocytes and adipocytes) and to exhibit immunosuppressive as well as healing capacities, through the secretion of paracrine mediators but also change surrounding cells metabolism through mitochondrial transfer. Several clinical trials in OA have shown modest improvement in pain and function and structural changes have not been shown. Research is needed to identify subgroup of progenitors, define role of EV and optimize cell product in order to develop efficient cell therapy for osteoarticular repair.

Submission Guidelines

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This Collection welcomes submission of Research Articles, Commentary, Letter, Method, Review, Short report, Viewpoint, Meeting report.

Before submitting your manuscript, please ensure you have read our submission guidelines. Articles for this collection should be submitted via our submission system, Editorial Manager. During the submission process you will be asked whether you are submitting to a collection, please select "Stromal cells and progenitor cells for osteoarticular regeneration" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they will handle through the peer review process. The peer review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.