Guest Editors:
Hui Zhang: Johns Hopkins University, USA
Yuanwei Xu: Johns Hopkins University, USA
Clinical Proteomics is calling for submissions to our Collection on Spatial proteomics.
Hui Zhang: Johns Hopkins University, USAHui Zhang graduated from Peking University with a BS and a MS degree, and from University of Pennsylvania with a Ph.D. degree. After working at New England Biolabs, Cell Signaling Technology, and the Institute for Systems Biology, she joined Johns Hopkins University in 2006. Her research interests focus on using quantitative proteomics and proteogenomics to understand the regulations and functions of proteins and protein modifications.
Yuanwei Xu: Johns Hopkins University, USAYuanwei Xu is a Ph.D. candidate in Chemical & Biomolecular Engineering at Johns Hopkins University. Her research focuses on developing innovative proteomics technologies, with a special emphasis on spatial proteomics and protein modifications. She has published several peer-reviewed papers and presented her research publicly at various conferences. Apart from her academic pursuits, she transforms her passion for engineering into mentoring students aspiring for an engineering career.
Although uterine serous carcinoma (USC) represents a small proportion of all uterine cancer cases, patients with this aggressive subtype typically have high rates of chemotherapy resistance and disease recurre...
Spatial proteomics is an emerging field that seeks to understand the spatial organization of proteins in organisms, systems, organs, tissues, or cellular compartments within cells. It is well-established that proteins perform their functions within specific spatial locations. The development of high-throughput proteomic methods for analyzing spatial localizations of proteins has led to rapid advances in our understanding of protein functions, and the advancement of computational tools for integrating spatial proteomics with other types of data is enabling the generation of more comprehensive mechanisms of molecular organizations in health and disease.
Spatial proteomics will further our understanding of protein expression, modifications, and complexes in different cellular or subcellular localization and their functions in cellular organization, signaling pathways, and disease mechanisms. It could also be used to develop new drug targets and to improve the efficacy of existing drug therapies. The objectives of this special issue are to highlight the current state of art in spatial proteomics, to introduce innovative spatial proteomic method development, and to gather the biological or clinical applications of spatial proteomics, which could propel the field to new heights.
Before submitting your manuscript, please ensure you have read our submission guidelines. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Spatial proteomics" from the dropdown menu.
Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.
The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.