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Regenerative medicine: focus on cartilage, discs and tendons

Guest Editors:

Gianfilippo Caggiari: (University of Sassari, Italy)
Liang Gao: (University of Saarland, Germany)
Eugenio Jannelli: (University of Campania "Luigi Vanvitelli", Italy) 
Giuseppe Rovere: (Agostino Gemelli University Polyclinic, Italy)
Payman Vahedi: (Islamic Azad University Medical Branch of Tehran, Iran)

This Collection is no longer accepting submissions. 

Musculoskeletal conditions will prevail in increasingly ageing populations, therefore, advanced cell therapies are needed. Tissue engineering, biomaterials and stem cells offer attractive options to repair and regenerate cartilage, intervertebral discs, ligaments, tendons and other connective tissues.

Meet the Guest Editors

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Gianfilippo Caggiari, University of Sassari, Italy

Dr. Gianfilippo Caggiari has a degree in Medicine and Surgery from the University of Sassari, with a specialisation in Orthopaedics and Traumatology. He is a Doctor of Orthopaedics and Traumatology, and an Assistant Professor in the Department of Medical, Surgical and Experimental Sciences of the University of Sassari.  

Liang Gao, University of Saarland, Germany

Dr. Liang Gao is currently the consultant in Orthopaedics and Surgical Oncology of the University Hospital of Anhui Medical University, China and the executive director of Huatuo Institute of Medical Innovation, China. He is the standing member of the Early Career Investigator committee of Osteoarthritis Research International (OARSI). He was the winner of the Basic Science Travelling Fellowship (2018) of International Cartilage Regeneration & Joint Preservation Society (ICRS) and served as the member (2019-2022) of the Basic Science Committee of ICRS. He was also the co-recipient of the Prize in Basic Science from the German Society for Orthopaedics and Trauma Surgery in both 2020 and 2021. He is the co-founder of the Sino Euro Orthopaedics Network (SEON), a non-profit platform for scientific exchange between Chinese and European orthopaedic professionals. He has authored over 60 peer-reviewed publications and his research focuses on the clinical development of advanced therapy medicinal products (ATMPs) for musculoskeletal conditions and solid tumours.

Eugenio Jannelli, University of Campania "Luigi Vanvitelli", Italy

Professor Eugenio Jannelli currently works as an Assistant Research Professor of Orthopaedic and Traumatology disease at "Università degli studi della Campania Luigi Vanvitelli" in Naples. During their training program, they spent periods as a clinical and research fellow abroad at "Hopitaux Universitaire de Geneve" and COF Lanzo Hospital, where he devoted himself to the study of hip arthroscopy and cartilage regeneration techniques.

Giuseppe Rovere, Agostino Gemelli University Polyclinic, Italy

After graduating in medicine and surgery, Dr. Giuseppe Rovere obtained their PhD. They currently work in Orthopaedics and Traumatology, at Fondazione Policlinico Universitario Agostino Gemelli, Rome. 

Payman Vahedi, Islamic Azad University Medical Branch of Tehran, Iran

Payman Vahedi is the chief of the department of Neurosurgery at "Farhikhtegan hospital" of Islamic Azad University in Tehran, Iran. Dr. Vahedi is a fellowship trained spine surgeon and neurosurgeon who is specialised in adult complex and minimally invasive spine surgeries. He obtained his medical degree from Mashad university of Medical Sciences and got the specialty degree with honours in Neurosurgery from Tabriz university of Medical Sciences. Dr. Vahedi did his fellowship training in spine surgery at Thomas Jefferson University (USA) and another fellowship in skull base surgery at University of Tubingen (Germany). He is the winner of multiple prestigious international fellowship awards from the "American Association of Neurological Surgeons'', 'Congress of Neurological Surgeons"; and "World Federation of Neurosurgical Societies". He is an active member of the educational and spine committees of the 'Neurosurgical Society of Iran" and has more than 40 publications in high impact international journals. Dr. Vahedi enjoys teaching, as well as research in the field of spine surgery. 

About the collection

Musculoskeletal conditions will prevail in increasingly ageing populations, therefore, advanced cell therapies are needed. Tissue engineering, biomaterials and stem cells offer attractive options to repair and regenerate cartilage, intervertebral discs, ligaments, tendons and other connective tissues.

This Collection encouraged submissions on the biology underlying pathophysiological and/or regenerative conditions. This Collection published new knowledge on disease progression states and potential targets to improve musculoskeletal healing. Basic molecular, animal models and applied clinical research papers were welcomed.

  1. Arthroscopic technique procedures was wide accepted for the treatment of chronic ankle instability (CAI). But little acknowledge was involved to the bony landmarks and anatomic features of different bundles of...

    Authors: Xin Xie, Linxin Chen, Cunshuai Fan, Shouyi Song, Yin Yu, Chen Jiao and Yanbin Pi
    Citation: BMC Musculoskeletal Disorders 2023 24:759
  2. Stem cell therapy has emerged as an effective treatment for multiple diseases, and some studies also demonstrate that it may be a promising treatment for osteoarthritis (OA). However, few studies have clarifie...

    Authors: Yunong Ao, Jiangjie Duan, Na Xiong, Nannan Qian, Rui Zhang, Liu Yang, Shicang Yu and Fuyou Wang
    Citation: BMC Musculoskeletal Disorders 2023 24:488
  3. One of the current choices of treatment for Trapeziometacarpal (TMC) joint arthritis is trapeziectomy with ligament reconstruction and tendon interposition arthroplasty. The Ceruso’s technique consists of comp...

    Authors: Marco Passiatore, Giuseppe Taccardo, Vitale Cilli, Giuseppe Rovere, Francesco Liuzza, Lucia Pannuto and Rocco De Vitis
    Citation: BMC Musculoskeletal Disorders 2023 24:328
  4. To explore the mechanism of the healing of tendon tissue and anti-adhesion, and to discuss the role of the transforming growth factor-β3 (TGF-β3)/cAMP response element binding protein-1 (CREB-1) signaling path...

    Authors: Li-Ming Wu, Yun-Jiao Wang, Shuai-Feng Li, Jing-Kun Wang, Jun Liu, Chao-Chao Fan and Yan Xiong
    Citation: BMC Musculoskeletal Disorders 2023 24:325
  5. 3D printing technology has become a research hotspot in the field of scientific research because of its personalized customization, maneuverability and the ability to achieve multiple material fabrications. Th...

    Authors: Yafei Wang, Chengzhen Ren, Fanggang Bi, Pengju Li and Ke Tian
    Citation: BMC Musculoskeletal Disorders 2023 24:151
  6. Intra-articular (IA) corticosteroid injection is recommended in refractory knee osteoarthritis patients. However, 40-mg of triamcinolone IA every 3 months for 2 years reduces cartilage volume as compared to sa...

    Authors: Komchan Utamawatin, Ong-art Phruetthiphat, Rit Apinyankul and Sumapa Chaiamnuay
    Citation: BMC Musculoskeletal Disorders 2023 24:92
  7. Mesenchymal stem cells (MSCs) possess the potential to differentiate into chondrocytes, which makes them an ideal source for healing cartilage defects. Here, we seek to identify the essential genes participati...

    Authors: Tongzhou Liang, Pengfei Li, Anjing Liang, Yuanxin Zhu, Xianjian Qiu, Jincheng Qiu, Yan Peng, Dongsheng Huang, Wenjie Gao and Bo Gao
    Citation: BMC Musculoskeletal Disorders 2022 23:985

Submission Guidelines

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This Collection welcomes submission of Research Articles. Before submitting your manuscript, please ensure you have read our submission guidelines. Articles for this Collection should be submitted via our submission system, SNAPP. During the submission process you will be asked whether you are submitting to a Collection, please select "Regenerative medicine: focus on cartilage, discs and tendons" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.