Journal of Inflammation is calling for submissions to our collection on Resolvins in resolution of Inflammation. Resolution of inflammation is an essential endogenous process that protects host tissues from a chronic inflammatory response. Resolution of inflammation is an active process, regulated by biochemical mediators and receptor-signaling pathways and driven by specialized pro-resolving mediators (SPM) derived from poly-unsaturated fatty acids (PUFA), including lipoxins, resolvins, (E and D series) protectins and maresins. In this collection we will discuss the crosstalk between resolution signals in the tissue response to injury has therapeutic application potential for preventing, maintaining, and regenerating chronically damaged tissues. These pathways may provide novel therapeutic protocols for autoimmune and autoinflammatory diseases, infection and trauma via regulation of cytokines, leucocyte trafficking and function.