In this issue of Genome Biology we present a special collection of Research, Method, Software, Review, Research Highlight and Editorial articles focusing on the theme of ‘the RBPome’, a term we use to describe RNA-binding proteins (RBPs) and their recognition elements within the transcriptome. The issue provides a number of new insights into the role of RBPs in gene regulation and incorporates studies using a variety of different approaches to assay RNA-protein interactions. Advances in computational analyses for the study of RBPome data are also reported. More information and perspective on our RBPome issue can be found on the BioMed Central blog.
