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Pyrexia in the ICU

Edited by Prof Lui Forni.

This series of articles, published in Critical Care, have not been sponsored. All articles have undergone the journal’s standard peer review process overseen by the Series Editor, with final decisions made by the Editor in Chief. The Series Editor and Editor in Chief declare no competing interests.

  1. Review

    Should we treat pyrexia? And how do we do it?

    The concept of pyrexia as a protective physiological response to aid in host defence has been challenged with the awareness of the severe metabolic stress induced by pyrexia. The host response to pyrexia varie...

    James F. Doyle and Frédérique Schortgen

    Critical Care 2016 20:303

    Published on: 3 October 2016

  2. Review

    Pyrexia: aetiology in the ICU

    Elevation in core body temperature is one of the most frequently detected abnormal signs in patients admitted to adult ICUs, and is associated with increased mortality in select populations of critically ill p...

    Daniel J. Niven and Kevin B. Laupland

    Critical Care 2016 20:247

    Published on: 1 September 2016

  3. Review

    The neurological and cognitive consequences of hyperthermia

    An elevated temperature has many aetiologies, both infective and non-infective, and while the fever of sepsis probably confers benefit, there is increasing evidence that the central nervous system is particula...

    Edward James Walter and Mike Carraretto

    Critical Care 2016 20:199

    Published on: 14 July 2016

  4. Review

    The pathophysiological basis and consequences of fever

    There are numerous causes of a raised core temperature. A fever occurring in sepsis may be associated with a survival benefit. However, this is not the case for non-infective triggers. Where heat generation ex...

    Edward James Walter, Sameer Hanna-Jumma, Mike Carraretto and Lui Forni

    Critical Care 2016 20:200

    Published on: 14 July 2016