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The Monte Carlo radiotherapy system PRIMO: Dosimetry and treatment planning research problems

The Monte Carlo system

Guest Edited by Dr Lorenzo Brualla and Dr Luca Cozzi

Monte Carlo simulation is the state-of-the-art for the study of radiation transport problems in radiotherapy, in particular for modelling medical linear accelerators (linacs). PRIMO is a software system based on the Monte Carlo method that simulates linacs and absorbed dose distributions in external beam radiotherapy patients. The software has been installed in nearly 300 hospitals and in about 100 universities worldwide. It is being used in the clinical practice, in dosimetry, and for educational and research applications. The aim of this series is to gather the advances in the aforementioned areas that have been achieved using PRIMO. Submission to the series is by invitation only from the Guest Editors.

Competing interests:

Dr Lorenzo Brualla declares he is one of the authors of the software PRIMO.

Please click here to submit a manuscript to this series.


  1. Content type: Research

    The software PRIMO for the Monte Carlo simulation of radiotherapy linacs could potentially act as a independent calculation system to verify the calculations of treatment planning systems. We investigated the ...

    Authors: Marcelino Hermida–López, David Sánchez–Artuñedo and Juan Francisco Calvo–Ortega

    Citation: Radiation Oncology 2018 13:144

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  2. Content type: Research

    To evaluate the difference of absorbed doses calculated to medium and to water by a Monte Carlo (MC) algorithm based treatment planning system (TPS), and to assess the potential clinical impact to dose prescri...

    Authors: Li Chen, Botian Huang, Xiaoyan Huang, Wufei Cao, Wenzhao Sun and Xiaowu Deng

    Citation: Radiation Oncology 2018 13:137

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  3. Content type: Research

    Linac output as a function of field sizes has a phantom and a head scatter component. This last term can be measured in-air with appropriate build-up ensuring a complete electron equilibrium and the absence of...

    Authors: A. Fogliata, A. Stravato, G. Reggiori, S. Tomatis, J. Würfel, M. Scorsetti and L. Cozzi

    Citation: Radiation Oncology 2018 13:126

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  4. Content type: Research

    A new implementation has been made on CloudMC, a cloud-based platform presented in a previous work, in order to provide services for radiotherapy treatment verification by means of Monte Carlo in a fast, easy ...

    Authors: Hector Miras, Rubén Jiménez, Álvaro Perales, José Antonio Terrón, Alejandro Bertolet, Antonio Ortiz and José Macías

    Citation: Radiation Oncology 2018 13:99

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  5. Content type: Review

    The use of the Monte Carlo (MC) method in radiotherapy dosimetry has increased almost exponentially in the last decades. Its widespread use in the field has converted this computer simulation technique in a co...

    Authors: Pedro Andreo

    Citation: Radiation Oncology 2018 13:121

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  6. Content type: Research

    IMRT provides higher dose conformation to the target and dose sparing to surrounding tissues than 3DCRT. Monte Carlo method in Medical Physics is not a novelty to approach dosimetric problems. A new PENELOPE b...

    Authors: Alessandro Esposito, Sofia Silva, Jorge Oliveira, Joana Lencart and João Santos

    Citation: Radiation Oncology 2018 13:91

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