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Ocular Biomechanics

Edited by: Ahmed Elsheikh

Ocular biomechanics received huge interest over the last decade. At the turn of the century, methods to characterise the mechanical properties of the cornea and sclera ex-vivo have, to a large extent, been primitive and hence unable to produce accurate or reliable information on the tissue’s hyperelasticity, hysteresis, viscoelasticity or anisotropy, and the situation was even worse with in-vivo methods.

Over the last 15 years, significant progress has been made on all fronts. There has been growing appreciation among clinicians and scientists alike of the importance of accurately characterising ocular tissue properties for customising treatment and management techniques for several conditions such as keratoconus, myopia and glaucoma. Methods to quantify the tissue’s response to mechanical actions ex-vivo have improved in sophistication and accuracy and become able to consider fully the dependence of mechanical behaviour on the distribution and orientation of collagen fibres. Numerical simulation saw huge advances to embed the material properties obtained in the laboratory in representative models of the eye and the clinical and surgical procedures applied to it. Methods to determine the tissue’s properties in-vivo have also received much attention and although we still do not have a working solution, we are not far from it.

The expectations for ocular biomechanics over the medium and long term are very positive in terms of both better understanding of tissue’s behaviour in health and disease and the customisation of procedures, clinical and surgical, for individual patients. This edition casts some light on new developments in this field and provides examples of the progress being made.

This series was published in Eye and Vision

  1. Research

    In vivo study of corneal responses to increased intraocular pressure loading

    The cornea is responsible for two-thirds of the eye's refractive power which is a function of the shape and refractive index. The aim of this present study is to examine human eyes in vivo for corneal shape ch...

    Ahmed Elsheikh, Charles W. McMonnies, Charles Whitford and Gavin C. Boneham

    Eye and Vision 2015 2:20

    Published on: 10 December 2015

  2. Research

    An experimental model of vitreous motion induced by eye rotations

    During eye rotations the vitreous humour moves with respect to the eye globe. This relative motion has been suggested to possibly have an important role in inducing degradation of the gel structure, which migh...

    Andrea Bonfiglio, Alberto Lagazzo, Rodolfo Repetto and Alessandro Stocchino

    Eye and Vision 2015 2:10

    Published on: 12 June 2015

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