Guest edited by Robert Colebunders, Robert Ryder, Patrick Suykerbuyk and Richard Idro
An article collection in Infectious Diseases of Poverty.
Nodding syndrome is a devastating epileptic syndrome appearing in previously healthy children between the ages of 5 and 18 years. The syndrome is characterized by head-nodding, an atonic seizure, and is often followed by tonic-clonic seizures, declining cognitive and motor function, psychiatric problems, stunting growth, physical deformities and early death. Until recently the cause of the syndrome was unknown. Therefore, no strategy for prevention and cure was possible. Recent studies have shown that nodding syndrome is only one of several clinical presentations of onchocerciasis-associated epilepsy (OAE) and that this form of epilepsy is present in all regions where onchocerciasis (river blindness) is poorly controlled. This series contains original papers about OAE research done in Uganda, Tanzania, Cameroon and the Democratic Republic of the Congo and review papers related to onchocerciasis and epilepsy.