Edited by:
Thomas Langmann: University of Cologne, Germany
Przemyslaw (Mike) Sapieha: University of Montreal, Canada
Journal of Neuroinflammation is calling for submissions to our new Collection on "Neuroinflammation in the Retina".
Image credit: Prof. Langmann
Retinal degenerative and neovascular diseases, including age-related macular degeneration (AMD), diabetic retinopathy (DR), glaucoma and rare monogenic dystrophies are major causes for global severe vision loss or blindness. In recent years, neuroinflammatory mechanisms have been identified as major factors for triggering the onset and progression of all these retinal diseases. Loss of retinal immune homeostasis is often accompanied by profound changes in cellular and humoral innate immunity and also involves adaptive immune responses by invading blood cell populations. We are only just beginning to understand the complex ocular inflammatory mechanisms and interplay between immune cells that occur in the eyes of patients with visual impairment.
This Collection seeks to discover novel immune mechanisms in the diseased retina that may offer novel diagnostic markers or highlight targets for immuno-modulatory therapies that could help to reduce the burden of vision loss worldwide.
As part of this Collection, we invite articles that cover the following topics:
• Role of resident and invading mononuclear phagocytes in the retina
• Role of T-cells and B-cells in retinal disease
• Complement factors in retinal disease
• Retinal pigment epithelium (RPE) inflammasome
• Immune responses in retinal gene therapy
• Microbiome and retinal immunity
• Retinal Immune memory and epigenetics
• Cellular senescence and retinal immune system
• Microglia-glia interactions in the retina
There are currently no articles in this collection.
This Collection welcomes submission of original Research Articles and Reviews. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Neuroinflammation in the Retina" from the dropdown menu.
Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.
The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.