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Nanomaterials to enhance the effect of ionizing radiation

Edited by Chun Li (MD Anderson Cancer Center USA) and Fred Currell (University of Manchester, UK)


The unique physicochemical properties of nanoparticles have made them especially attractive for mediating enhanced antitumor activity with various energy sources, such as light, magnetic field, radiofrequency, microwave, and ionizing radiation. Enhancement of radioresponse with nanoparticles is attributed to increased drug delivery, synergist interaction with different modes of cell killing, and/or increased cellular exposure to ionizing radiation beams. This collection in Cancer Nanotechnology aims to cover a broad scope of current research on the interaction between nanoparticles and radiation, and provide an outlook for clinical translation of nanotechnology in radiotherapy, one of the pillars of anticancer therapies.

Before submitting your manuscript, please ensure you have carefully read the submission guidelines for Cancer Nanotechnology.

New articles in the collection will be added here as they are published.

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  1. The combined use of radiation therapy and chemotherapy is commonly being used in cancer treatment. The side effects of the treatment can be further minimized through targeted delivery of anticancer drugs and l...

    Authors: Celina Yang, Kyle Bromma, Caterina Di Ciano-Oliveira, Gaetano Zafarana, Monique van Prooijen and Devika B. Chithrani
    Citation: Cancer Nanotechnology 2018 9:4
    Content type: Research Published on:

  3. Small metallic nanoparticles are proposed as potential nanodrugs to optimize the performances of radiotherapy. This strategy, based on the enrichment of tumours with nanoparticles to amplify radiation effects ...

    Authors: Sha Li, Erika Porcel, Hynd Remita, Sergio Marco, Matthieu Réfrégiers, Murielle Dutertre, Fabrice Confalonieri and Sandrine Lacombe
    Citation: Cancer Nanotechnology 2017 8:4
    Content type: Research Published on:

  5. Radiotherapy has been an integral treatment modality for cancer. The field arose from and progressed through innovations in physics, engineering, and biology. The evolution of radiation oncology will rely on t...

    Authors: Yu Mi, Zhiying Shao, Johnny Vang, Orit Kaidar-Person and Andrew Z. Wang
    Citation: Cancer Nanotechnology 2016 7:11
    Content type: Review Published on:

  7. Radiotherapy is currently used in around 50% of cancer treatments and relies on the deposition of energy directly into tumour tissue. Although it is generally effective, some of the deposited energy can advers...

    Authors: Kaspar Haume, Soraia Rosa, Sophie Grellet, Małgorzata A. Śmiałek, Karl T. Butterworth, Andrey V. Solov’yov, Kevin M. Prise, Jon Golding and Nigel J. Mason
    Citation: Cancer Nanotechnology 2016 7:8
    Content type: Review Published on: