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Neurocritical care

Edited by Fabio Silvo Taccone

Adequate treatment of patients with acute brain injury aims to optimize cerebral perfusion as to minimize the occurrence of secondary injuries. However, several questions on the optimal management still remain unanswered. In this review series published in Critical Care, the appropriate use of sedative and analgesic agents will be discussed; indeed, sedation may provide some neuroprotection in the most severe patients but it should be also interrupted to allow clinical daily examination. Similarly, the best approach to guide fluid administration and blood transfusion will be accurately examined. The important issue of the regulation and bedside assessment of cerebral circulation may provide significant proposals in order to avoid cerebral hypoperfusion in these patients. Finally, the management of cerebral vasospasm after subarachnoid haemorrhage, which remains one of the main causes of poor neurological outcome, will be discussed.

  1. Review

    Anemia management after acute brain injury

    Anemia is frequent among brain-injured patients, where it has been associated with an increased risk of poor outcome. The pathophysiology of anemia in this patient population remains multifactorial; moreover, ...

    Christophe Lelubre, Pierre Bouzat, Ilaria Alice Crippa and Fabio Silvio Taccone

    Critical Care 2016 20:152

    Published on: 17 June 2016

  2. Review

    Fluid management of the neurological patient: a concise review

    Maintenance fluids in critically ill brain-injured patients are part of routine critical care. Both the amounts of fluid volumes infused and the type and tonicity of maintenance fluids are relevant in understa...

    Mathieu van der Jagt

    Critical Care 2016 20:126

    Published on: 31 May 2016

  3. Review

    Optimizing sedation in patients with acute brain injury

    Daily interruption of sedative therapy and limitation of deep sedation have been shown in several randomized trials to reduce the duration of mechanical ventilation and hospital length of stay, and to improve ...

    Mauro Oddo, Ilaria Alice Crippa, Sangeeta Mehta, David Menon, Jean-Francois Payen, Fabio Silvio Taccone and Giuseppe Citerio

    Critical Care 2016 20:128

    Published on: 5 May 2016